PLoS ONE, 2023 ObjectiveThis study compared the dynamic susceptibility contrast (DSC) magnetic resonance imaging parameters and apparent diffusion coefficient (ADC) between pilocytic astrocytoma (PA) and diffuse midline glioma, H3K27-altered (DMG) variants.MethodsThe ...
Ryo Kurokawa +5 more
doaj +1 more source
Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International and European Society for Pediatric Oncology DIPG registries [PDF]
, 2018 Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median survival of < 1 year. The International and European Society for Pediatric Oncology DIPG Registries collaborated to compare clinical, radiologic, and ...
Antonelli, Manila +73 more
core +4 more sources
Histone H3.1 (S28Phospho) IP for MS v1
, 2021 Immunoprecipitation of Histone H3 S28ph for mass spectrometry.
Cameron Lloyd-Jones +2 more
openaire +1 more source
Evidence for the nuclear import of histones H3.1 and H4 as monomers [PDF]
The EMBO Journal, 2018 Newly synthesised histones are thought to dimerise in the cytosol and undergo nuclear import in complex with histone chaperones. Here, we provide evidence that human H3.1 and H4 are imported into the nucleus as monomers. Using a tether-and-release system to study the import dynamics of newly synthesised histones, we find that cytosolic H3.1 and H4 can ...
Michael James Apta‐Smith +2 more
openaire +3 more sources
Dynamic deposition of histone variant H3.3 accompanies developmental remodeling of the Arabidopsis transcriptome. [PDF]
PLoS Genetics, 2012 In animals, replication-coupled histone H3.1 can be distinguished from replication-independent histone H3.3. H3.3 variants are enriched at active genes and their promoters. Furthermore, H3.3 is specifically incorporated upon gene activation.
Heike Wollmann +5 more
doaj +1 more source
Biomedicines, 2023 Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by HIST1H3B and HIST1H3C) and H3.3 (encoded by H3F3A), are mainly associated with pediatric brain cancers ...
Benedicte Grebstad Tune +20 more
doaj +1 more source
Maximum principle for a stochastic delayed system involving terminal state constraints [PDF]
, 2017 We investigate a stochastic optimal control problem where the controlled system is depicted as a stochastic differential delayed equation; however, at the terminal time, the state is constrained in a convex set.
Shi, Yufeng, Wen, Jiaqiang
core +3 more sources
Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle [PDF]
Nucleic Acids Research, 2014 Lineage potential is triggered by lineage-specific transcription factors in association with changes in the chromatin structure. Histone H3.3 variant is thought to play an important role in the regulation of lineage-specific genes. To elucidate the function of H3.3 in myogenic differentiation, we forced the expression of GFP-H3.1 to alter the balance ...
Akihito Harada +6 more
openaire +2 more sources
Auxin and epigenetic regulation of SKP2B, an F-box that represses lateral root formation [PDF]
, 2012 In plants, lateral roots originate from pericycle founder cells that are specified at regular intervals along the main root. Here, we show that Arabidopsis (Arabidopsis thaliana) SKP2B (for S-Phase Kinase-Associated Protein2B), an F-box protein ...
Beeckman, Tom +9 more
core +2 more sources
Characterizing circulating nucleosomes in the plasma of dogs with lymphoma
BMC Veterinary Research, 2021 Background Nucleosomes consist of DNA wrapped around a histone octamer core like beads on a string so that DNA can be condensed as chromatin into chromosomes.
Christopher Dolan +6 more
doaj +1 more source