Frontiers in Medicine, 2023 PurposePredicting H3.1, TP53, and ACVR1 mutations in DIPG could aid in the selection of therapeutic options. The contribution of clinical data and multi-modal MRI were studied for these three predictive tasks.
Fahad Khalid +13 more
doaj +1 more source
Cross-connection management specialisation for WDM-OTN's [PDF]
, 2000 WDM optical transport networks (WDM-OTN) will use new all-optical nodes that will perform functions in the optical domain, using wavelength as a new network resource.
Comellas Colomé, Jaume +3 more
core +1 more source
Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells. [PDF]
PLoS ONE, 2014 Genome-wide distribution of the majority of H2A and H3 variants (H2A, H2AX, H2AZ, macroH2A, H3.1, H3.2 and H3.3) was simultaneously investigated in mouse embryonic stem cells by chromatin immunoprecipitation sequencing.
Masashi Yukawa +10 more
doaj +1 more source
Approximations to the two-hole ground state of the Hubbard-Anderson model: a numerical test [PDF]
, 1995 Several resonating-valence-bond-type states are being considered as an approximation of the two-hole ground state of the two-dimensional Hubbard-Anderson model.
Caspers, W.J. +2 more
core +3 more sources
H3.3-H4 tetramer splitting events feature cell-type specific enhancers. [PDF]
PLoS Genetics, 2013 Previously, we reported that little canonical (H3.1-H4)(2) tetramers split to form "hybrid" tetramers consisted of old and new H3.1-H(4) dimers, but approximately 10% of (H3.3-H4)2 tetramers split during each cell cycle.
Chang Huang +7 more
doaj +1 more source
Using a task-based approach in evaluating the usability of BoBIs in an e-book environment [PDF]
, 2008 This paper reports on a usability evaluation of BoBIs (Back-of-the-book Indexes) as searching and browsing tools in an e-book environment. This study employed a task-based approach and within-subject design.
B.C. Bennion +15 more
core +1 more source
Molecular basis of the selective methylation of histone H3.1 [PDF]
Acta Crystallographica Section A Foundations and Advances, 2014 Histone proteins are critical components of the chromatin fiber. With the exception of histone H4, histone proteins exist as different variants with assigned specialized functions and are proposed to act as key elements for the selective deposition of histone post-translational modifications (PTMs).
openaire +1 more source
H3.1/3.2 regulate the initial progression of the gene expression program. [PDF]
Nucleic Acids ResAbstract In mice, transcription from the zygotic genome is initiated at the mid-one-cell stage, and occurs promiscuously in many areas of the genome, including intergenic regions. Regulated transcription from selected genes is established during the two-cell stage.
Funaya S +4 more
europepmc +3 more sources
Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila [PDF]
, 2019 Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin.
Pearlman, Ronald E. +7 more
core +1 more source
Replication‐coupled histone H3.1 deposition determines nucleosome composition and heterochromatin dynamics during Arabidopsis seedling development [PDF]
New Phytologist, 2018 Summary Developmental phase transitions are often characterized by changes in the chromatin landscape and heterochromatin reorganization. In Arabidopsis, clustering of repetitive heterochromatic loci into so‐called chromocenters is an important determinant of chromosome organization in nuclear space.
Benoit, Matthias +8 more
openaire +3 more sources