Results 181 to 190 of about 16,775 (201)
The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis. [PDF]
Day CA +13 more
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SUMO operates from a unique long tandem repeat to keep innate immunity in check. [PDF]
Goffeney A +9 more
europepmc +1 more source
The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis.
Nunez-Vazquez R +5 more
europepmc +1 more source
Vif- H3.3 interaction, a new Vif function?
Silva, Alexandra Maia e +3 more
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Histone variants H3.3 and H2A.Z/H3.3 facilitate excision of uracil from nucleosome core particles
DNA Repair, 2022At the most fundamental level of chromatin organization, DNA is packaged as nucleosome core particles (NCPs) where DNA is wound around a core of histone proteins. This ubiquitous sequestration of DNA within NCPs presents a significant barrier to many biological processes, including DNA repair.
Chuxuan, Li +2 more
openaire +2 more sources
Histone H3.3 G34-mutant Diffuse Gliomas in Adults
American Journal of Surgical Pathology, 2021The characteristics of H3.3 G34-mutant gliomas in adults have yet to be specifically described. Thirty adults with H3.3 G34-mutant diffuse gliomas were retrospectively reviewed for clinical and pathologic information. Molecular profiling using next-generation sequencing was performed in 29 of the 30 H3.3 G34-mutant patients with 1 patient lacking ...
Leiming, Wang +14 more
openaire +2 more sources
Characterization of mouse H3.3-like histone genes
Gene, 1987We designed a strategy to select genomic clones of mouse replication-independent H3.3 histone genes. We obtained three clones which met our selection criteria for being H3.3 genes. Upon sequencing two of these clones we found that they were unlike previously isolated chicken H3.3 clones: they code for several unpredicted amino acid substitutions and ...
S E, Wellman +4 more
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Transcription-coupled H3.3 recycling: A link with chromatin states
Seminars in Cell & Developmental Biology, 2023Histone variant H3.3 is incorporated into chromatin throughout the cell cycle and even in non-cycling cells. This histone variant marks actively transcribed chromatin regions with high nucleosome turnover, as well as silent pericentric and telomeric repetitive regions.
Delaney, Kamila, Almouzni, Geneviève
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Biochemical and Biophysical Research Communications, 2015
Replication-independent histone variant H3.3 is incorporated into distinct genomic regions including promoters. However topology of promoter-associated H3.3 in relation to chromatin modifications and transcriptional outcome is not known, providing no insight on any distinction between H3.3-containing active and inactive promoters.
Eivind G, Lund +2 more
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Replication-independent histone variant H3.3 is incorporated into distinct genomic regions including promoters. However topology of promoter-associated H3.3 in relation to chromatin modifications and transcriptional outcome is not known, providing no insight on any distinction between H3.3-containing active and inactive promoters.
Eivind G, Lund +2 more
openaire +2 more sources
Genome-scale profiling of histone H3.3 replacement patterns
Nature Genetics, 2005Histones of multicellular organisms are assembled into chromatin primarily during DNA replication. When chromatin assembly occurs at other times, the histone H3.3 variant replaces canonical H3. Here we introduce a new strategy for profiling epigenetic patterns on the basis of H3.3 replacement, using microarrays covering roughly one-third of the ...
Yoshiko, Mito +2 more
openaire +2 more sources

