Results 61 to 70 of about 16,775 (201)

Relationships between attachment insecurity, beliefs about the self and others, paranoia, and social functioning across the psychosis continuum

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Self‐beliefs and other‐regarding beliefs are related to attachment experiences and may contribute to paranoid beliefs and social functioning difficulties in psychosis. However, their relationships have not been examined jointly from an ecological perspective, while considering different degrees of psychosis risk.
Pilar de‐la‐Higuera‐Gonzalez, Carsten Allefeld, Alejandro de‐la‐Torre‐Luque, Ana Isabel Guillén, Marina Díaz‐Marsá, Anne‐Kathrin Fett   +5 more
wiley   +1 more source

Histone H1 binding is inhibited by histone variant H3.3 [PDF]

The EMBO Journal, 2009
Linker histones are involved in the formation of higher-order chromatin structure and the regulation of specific genes, yet it remains unclear what their principal binding determinants are. We generated a genome-wide high-resolution binding map for linker histone H1 in Drosophila cells, using DamID. H1 binds at similar levels across much of the genome,
Ulrich, Braunschweig, Greg J, Hogan, Ludo, Pagie, Bas, van Steensel   +3 more
openaire   +2 more sources

Plasma cell differentiation is regulated by the expression of histone variant H3.3

Nature Communications
The differentiation of B cells into plasma cells is associated with substantial transcriptional and epigenetic remodeling. H3.3 histone variant marks active chromatin via replication-independent nucleosome assembly.
Yuichi Saito, Akihito Harada, Miho Ushijima, Kaori Tanaka, Ryota Higuchi, Akemi Baba, Daisuke Murakami, Stephen L. Nutt, Takashi Nakagawa, Yasuyuki Ohkawa, Yoshihiro Baba   +10 more
doaj   +1 more source

Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells. [PDF]

PLoS ONE, 2014
Genome-wide distribution of the majority of H2A and H3 variants (H2A, H2AX, H2AZ, macroH2A, H3.1, H3.2 and H3.3) was simultaneously investigated in mouse embryonic stem cells by chromatin immunoprecipitation sequencing.
Masashi Yukawa, Tomohiko Akiyama, Vedran Franke, Nathan Mise, Takayuki Isagawa, Yutaka Suzuki, Masataka G Suzuki, Kristian Vlahovicek, Kuniya Abe, Hiroyuki Aburatani, Fugaku Aoki   +10 more
doaj   +1 more source

Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma [PDF]

, 2017
Recent exciting work partly through The Cancer Genome Atlas has implicated epigenetic mechanisms including histone modifications in the development of both pediatric and adult high-grade glioma (HGG).
Kurian, Kathreena M, Lowis, Stephen P, Malik, Karim, Singleton, Will G B, Williams, Maria J   +4 more
core   +1 more source

Integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant reveals universal TP53 abnormalities

Brain Pathology, EarlyView.
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez, Cinthya Zepeda Mendoza, Thomas M. Kollmeyer, Kristen L. Drucker, Vanessa M. Pazdernik, Paul A. Decker, Corinne E. Praska, Jayson Hardcastle, Stephanie Smoley, Matthew Isaacson, Mallika Gandham, Surendra Dasari, Aditya Raghunathan, Caterina Giannini, Gang Zheng, Aaron Wagner, M. Beatriz Lopes, Kar‐Ming A. Fung, JoElle G. Peterson, Andreana L. Rivera, Christopher Rossi, Meggen A. Walsh, Zied Abdullaev, Kenneth Aldape, Martha Quezado, Drew Pratt, Patrick Joseph Cimino, Robert B. Jenkins, Cristiane M. Ida   +28 more
wiley   +1 more source

The localization of histone H3.3 in germ line chromatin of Drosophila males as established with a histone H3.3-specific antiserum [PDF]

Chromosoma, 1997
A rabbit antiserum, specific for the histone H3.3 replacement variant, was raised with the aid of a histone H3.3-specific peptide. Immuno blot experiments demonstrated the specificity of this polyclonal antiserum. In addition, we showed on immuno blots that two monoclonal antibodies isolated from mice with systemic lupus erythematosus (SLE) display ...
Akhmanova, A.S., Miedema, K., Wang, X., Bruggen, M.C.J. van, Berden, J.H.M., Moudrianakis, E.N., Hennig, W.H.G.   +6 more
openaire   +4 more sources

Replication-Uncoupled Histone Deposition during Adenovirus DNA Replication [PDF]

, 2012
In infected cells, the chromatin structure of the adenovirus genome DNA plays critical roles in its genome functions. Previously, we reported that in early phases of infection, incoming viral DNA is associated with both viral core protein VII and ...
Komatsu Tetsuro, Nagata Kyosuke, 小松 哲郎, 永田 恭介   +3 more
core   +1 more source

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

The FEBS Journal, EarlyView.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause, Marco Borsò, Marisa Müller, Axel Imhof, Zivkos Apostolou, Peter B. Becker   +5 more
wiley   +1 more source

Dynamic replacement of histone H3 variants reprograms epigenetic marks in early mouse embryos. [PDF]

PLoS Genetics, 2011
Upon fertilization, reprogramming of gene expression is required for embryo development. This step is marked by DNA demethylation and changes in histone variant composition.
Tomohiko Akiyama, Osamu Suzuki, Junichiro Matsuda, Fugaku Aoki   +3 more
doaj   +1 more source