Results 81 to 90 of about 16,775 (201)

Who Supports the Digitalization of Education? New Survey Evidence From Six OECD Countries

Regulation &Governance, EarlyView.
ABSTRACT This paper investigates how citizens perceive and evaluate the digitalization of education. Drawing on original survey data from six OECD countries (Germany, Japan, Poland, Spain, Sweden, and the US), the study addresses the overarching question: Does public opinion support or inhibit the digital transformation of education?
Marius R. Busemeyer
wiley   +1 more source

Chd2 interacts with H3.3 to determine myogenic cell fate [PDF]

The EMBO Journal, 2012
Cell differentiation is mediated by lineage-determining transcription factors. We show that chromodomain helicase DNA-binding domain 2 (Chd2), a SNF2 chromatin remodelling enzyme family member, interacts with MyoD and myogenic gene regulatory sequences to specifically mark these loci via deposition of the histone variant H3.3 prior to cell ...
Harada, Akihito, Okada, Seiji, Konno, Daijiro, Odawara, Jun, Yoshimi, Tomohiko, Yoshimura, Saori, Kumamaru, Hiromi, Saiwai, Hirokazu, Tsubota, Toshiaki, Kurumizaka, Hitoshi, Akashi, Koichi, Tachibana, Taro, Imbalzano, Anthony N., Ohkawa, Yasuyuki   +13 more
openaire   +3 more sources

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Molecular & Cellular Proteomics, 2022
Chromatin structure, transcription, DNA replication, and repair are regulated via locus-specific incorporation of histone variants and posttranslational modifications that guide effector chromatin-binding proteins. Here we report unbiased, quantitative interactomes for the replication-coupled (H3.1) and replication-independent (H3.3) histone H3 ...
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins   +8 more
openaire   +4 more sources

HIRA vs. DAXX: the two axes shaping the histone H3.3 landscape

Experimental and Molecular Medicine
H3.3, the most common replacement variant for histone H3, has emerged as an important player in chromatin dynamics for controlling gene expression and genome integrity.
Jinmi Choi, Taewan Kim, Eun-Jung Cho
doaj   +1 more source

Global H3.3 dynamic deposition defines its bimodal role in cell fate transition

Nature Communications, 2018
Histone variant H3.3 is incorporated at transcriptionally active genes and is associated with active marks. Here, the authors investigate H3.3 deposition during reprogramming and find that initially H3.3 helps maintain parental cell fate and is later ...
Hai-Tong Fang, Chadi A. EL Farran, Qiao Rui Xing, Li-Feng Zhang, Hu Li, Bing Lim, Yuin-Han Loh   +6 more
doaj   +1 more source

Math Anxiety and Its Relations to Arithmetic Fluency and Number Processing: Evidence From Finnish, Finnish‐Swedish, and Swedish Fourth‐Grade Students

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT The negative relationship between math anxiety and mathematics performance is well established. However, factors such as how math anxiety is operationalized, the specific mathematical domain, gender, and cultural context may influence this relationship.
Pinja Tähti, Jonatan Finell, Anna Tapola, Ellen Sammallahti, Anna Widlund, Bert Jonsson, Riikka Mononen, Johan Korhonen   +7 more
wiley   +1 more source

Nucleosome stability mediated by histone variants H3.3 and H2A.Z [PDF]

Genes & Development, 2007
Nucleosomes containing the histone variant H3.3 tend to be clustered in vivo in the neighborhood of transcriptionally active genes and over regulatory elements. It has not been clear, however, whether H3.3-containing nucleosomes possess unique properties that would affect transcription.
Chunyuan, Jin, Gary, Felsenfeld
openaire   +2 more sources

Realizations of Galilei algebras

, 2016
All inequivalent realizations of the Galilei algebras of dimensions not greater than five are constructed using the algebraic approach proposed by I. Shirokov.
Nesterenko, Maryna, Posta, Severin, Vaneeva, Olena   +2 more
core   +1 more source

HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes. [PDF]

, 2012
BACKGROUND: Nuclear reprogramming is potentially important as a route to cell replacement and drug discovery, but little is known about its mechanism. Nuclear transfer to eggs and oocytes attempts to identify the mechanism of this direct route towards ...
Almouzni, Genevieve, Astrand, Carolina, Garrett, Nigel, Gurdon, John B, Jullien, Jerome, Szenker, Emmanuelle   +5 more
core   +3 more sources

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source