Results 211 to 220 of about 5,643 (237)

Multi-omics landscape of alternative splicing in diffuse midline glioma reveals immune- and neural-driven subtypes with implications for spliceosome-targeted therapy. [PDF]

Front Immunol
Liu C, Liu Y, Lin H, Zhang C, Zhang B, Song H, Fan X, Lyu Y, Yang H, Mao Y.   +9 more
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Targeting the Mitochondria in High-Grade Gliomas. [PDF]

Cancers (Basel)
Sathe S, Li Q, Jung J, Wu J.
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<i>H3K27M-</i> and <i>BRAF V600E</i>-Altered gliomas and glioneuronal tumors-clinico-pathologic and radiologic perspective in a cohort treated with targeted therapy. [PDF]

Neurooncol Adv
Chen CG, Rameh V, Rosenberg T, Yeo KK, Chi S, Wright KD, Baird LC, Filbin MG, Fehnel KP, Abdullaev Z, Aldape KD, Lidov HG, Alexandrescu S.   +12 more
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GABAergic neuron-to-glioma synapses in diffuse midline gliomas. [PDF]

Nature
Barron T, Yalçın B, Su M, Byun YG, Gavish A, Shamardani K, Xu H, Ni L, Soni N, Mehta V, Maleki Jahan S, Kim YS, Taylor KR, Keough MB, Quezada MA, Geraghty AC, Mancusi R, Vo LT, Castañeda EH, Woo PJ, Petritsch CK, Vogel H, Kaila K, Monje M.   +23 more
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Beyond the DNA sequence: mapping the dynamic epigenetic landscape for risk stratification and therapeutic intervention in acute myeloid leukemia. [PDF]

Clin Exp Med
Xie J, Soleimani Samarkhazan H.
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A rare case of adult H3 K27-altered diffuse midline glioma with multifocal cerebrospinal fluid disseminated disease. [PDF]

Radiol Case Rep
Chen J, Conyngham S, Bayly A, McMaster J, Trang J.   +4 more
europepmc   +1 more source

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H3K27M mutation in adult cerebellar glioblastoma

Journal of Clinical Neuroscience, 2020
A methionine substitution of lysine at residue 27 of histone H3 (H3K27M) mutation has become synonymous with malignant pediatric diffuse midline glioma (DMG), that occurs commonly in the brainstem. Therefore, recent reports that this same mutation occurs in malignant adult glioblastoma (GBM) located in the cerebellum are both unexpected and intriguing.
Victor M, Lu, Oluwaseun O, Akinduro, David J, Daniels   +2 more
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