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Fatal human H3N8 influenza virus has a moderate pandemic risk. [PDF]

open access: yesPLoS Pathogens
In China, low pathogenic avian influenza (LPAI) H3N8 virus is widespread among chickens and has recently caused three zoonotic infections, with the last one in 2023 being fatal.
Valerie Le Sage   +16 more
doaj   +2 more sources

Will influenza A(H3N8) cause a major public health threat?

open access: yesInternational Journal of Infectious Diseases, 2022
The diversity of zoonotic influenza viruses and their ability to cross the species barrier has always been alarming and requires continuous surveillance in both human and animal populations.
Hadi M Yassine, Maria Smatti
exaly   +3 more sources

Epidemiological Investigation and Characterization of Avian Influenza A H3N8 Virus in Guangdong Province, China [PDF]

open access: yesAnimals
The H3N8 low pathogenic avian influenza virus (LPAIV) exhibits broad host tropism, infecting diverse avian and mammalian species, raising concerns about its zoonotic potential.
Junjie Lin   +8 more
doaj   +2 more sources

Prevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021

open access: yesEmerging Microbes and Infections, 2023
The continued evolution and emergence of novel influenza viruses in wild and domestic animals poses an increasing public health risk. Two human cases of H3N8 avian influenza virus infection in China in 2022 have caused public concern regarding the risk ...
Xuyong Li, Mengjing Wang, Dong Chu
exaly   +3 more sources

Two kinds of novel reassortment H3 subtypes of avian influenza viruses: similar genetic composition, different mammalian transmission capabilities [PDF]

open access: yesPoultry Science
To assess the potential threat of the novel H3 subtype Avian Influenza Virus (AIV) to the poultry industry and human health, whole-genome sequencing and phylogenetic tree and homology analysis were conducted on four H3N3 viruses and one H3N8 virus ...
Xinyu Han   +13 more
doaj   +2 more sources

PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals

open access: yesEmerging Microbes and Infections, 2021
Influenza H3N8 viruses have been recovered frequently from wild bird species, including Anseriformes (primarily from migratory ducks) and Charadriiformes (primarily from shorebirds). However, little attention has been given to the transmission ability of
Songtao Yang   +2 more
exaly   +3 more sources

From Surfaces to Spillover: Environmental Persistence and Indirect Transmission of Influenza A(H3N8) Virus [PDF]

open access: yesMicroorganisms
Avian influenza viruses (AIVs) pose a significant zoonotic threat, with the emerging H3N8 subtype raising increasing concern due to sporadic human infections. Current strategies for risk assessment of novel AIVs primarily rely on genetic surveillance and
Yifei Jin   +13 more
doaj   +2 more sources

Structural basis of receptor-binding adaptation of human-infecting H3N8 influenza A virus [PDF]

open access: yesJournal of Virology
Recent avian-origin H3N8 influenza A virus (IAV) that have infected humans pose a potential public health concern. Alterations in the viral surface glycoprotein, hemagglutinin (HA), are typically required for IAVs to cross the species barrier for ...
Tianjiao Hao   +8 more
doaj   +2 more sources

Phylogenetic Analysis and Characterization of a Sporadic Isolate of Equine Influenza A H3N8 from an Unvaccinated Horse in 2015

open access: yesViruses, 2018
Equine influenza, caused by the H3N8 subtype, is a highly contagious respiratory disease affecting equid populations worldwide and has led to serious epidemics and transboundary pandemics.
Chithra Chembil Sreenivasan   +2 more
exaly   +3 more sources

Virulence and transmission characteristic of H3N8 avian influenza virus circulating in chickens in China [PDF]

open access: yesVirulence
Influenza H3N8 viruses have been frequently isolated from chicken farms. However, comprehensive characterization of their virological properties, molecular evolution, virulence, and risk of spillover into mammals remains limited.
Mei Mei   +4 more
doaj   +2 more sources

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