Results 41 to 50 of about 601 (134)

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Targets of influenza human T-cell response are mostly conserved in H5N1

mBio
Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns over a possible future pandemic.
John Sidney, A-Reum Kim, Rory D. de Vries, Bjoern Peters, Philip S. Meade, Florian Krammer, Alba Grifoni, Alessandro Sette   +7 more
doaj   +1 more source

Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation Plumas y gripe: identificación de datos faltantes en la dinámica de hospedadores de la influenza aviar para priorizar la conservación de la vida silvestre

Wildlife Monographs, Volume 225, Issue 1, September 2026.
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey, Matthew Gonnerman, Shenglai Yin, Cody M. Kent, Joshua Cullen, Jeffery D. Sullivan, Jonathan B. Dain, Nichola J. Hill, Diann J. Prosser, Jennifer M. Mullinax   +9 more
wiley   +1 more source

Between‐species contagion drives HPAI transmission and mass mortality in seabirds

Journal of Animal Ecology, Volume 95, Issue 8, Page 1488-1503, August 2026.
Modelling the unprecedented avian panzootic caused by High‐Pathogenicity Avian Influenza (HPAI) across the Northeast Atlantic gannet breeding metapopulation, we estimated 28% (95% CI: 21%–34%) HPAI‐related mortality. Large‐scale outbreak initiation was best explained by external infection sources, most likely, other seabird species.
Jason Matthiopoulos, Stephen Votier, Sarah Wanless, Emma Cunningham, Jude V. Lane, Jana W. E. Jeglinski   +5 more
wiley   +1 more source

Multiplex real-time reverse transcription polymerase chain reaction for differential detection of H5, N1, and N8 genes of highly pathogenic avian influenza viruses

Veterinární Medicína, 2017
Rapid and differential diagnosis of highly pathogenic avian influenza virus (HPAIV) subtype H5 is essential for the effective prevention and control of outbreaks caused by this pathogen.
Y.R. Park, E.M. Kim, Y.J. Lee, S.G. Yeo, C.K. Park   +4 more
doaj   +1 more source

Highly pathogenic avian influenza (A/H5N1) virus outbreaks in Lesotho, May 2021

Emerging Microbes and Infections, 2022
In May 2021, Lesotho reported its first outbreak of highly pathogenic avian influenza (HPAI) to the OIE. Samples were collected from infected poultry and the virus was confirmed by molecular tests to be of the H5N1 subtype.
Mabusetsa R.J. Makalo, William G. Dundon, Tirumala B.K. Settypalli, Sneha Datta, Charles E. Lamien, Giovanni Cattoli, Moeketsi S. Phalatsi, Relebohile J. Lepheana, Mpaliseng Matlali, Relebohile G. Mahloane, Marosi Molomo, Palesa C. Mphaka   +11 more
doaj   +1 more source

Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley   +1 more source

Identification of Gene Resistance to Avian InfluenzaVirus (Mx Gene) among Wild Waterbirds

Makara Seri Sains, 2013
The Mx gene is an antiviral gene used to determine the resistance or the susceptibility to different types of viruses, including the Avian Influenza (AI) virus subtype H5N1. The AI virus subtype H5N1 infection in chickens causes Mx gene polymorphism. The
Dewi Elfidasari, Dedy Duryadi Solihin, Retno Damayanti Soejoedono, Sri Murtini   +3 more
doaj  

An Outbreak of Highly Pathogenic Avian Influenza Subtype H5N1 in Broiler Breeders, Korea

Journal of Veterinary Medical Science, 2005
Highly pathogenic avian influenza (HPAI) was diagnosed in broiler breeders, submitted to the National Veterinary Research and Quarantine Service in South Korea. Grossly, the dead breeders had lesions consistent with HPAI, including pancreatic mottling, splenomegaly, pulmonary edema and congestion, and hemorrhages in the mucosa of the proventriculus ...
KWON, Yong-kuk, SUNG, Haan-woo, JOH, Sung-jun, LEE, Youn-jeong, KIM, Min-chul, CHOI, Jun-gu, LEE, Eun-kyoung, WEE, Sung-Hwan, KIM, Jae-hong   +8 more
openaire   +3 more sources