Results 31 to 40 of about 107 (96)

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Mild environmental stress inoculation promotes resilience to anxiety in female rats

Scientific Reports
Stress inoculation refers to exposure to mild stressors that promote resilience to future stress. However, the optimal intensity and nature of prior stress required for this effect remain unclear.
Hiroko Mochizuki-Kawai, Tingbi Xiong, Michimasa Toyoshima, Seita Nakazawa, Hideaki Oike, Hiromi Kimoto, Satoru Tomita, Kazuo Yamada   +7 more
doaj   +1 more source

Genome‐Wide Analysis Successfully Resolves Population Structure Shaped by Recent Divergence in the Endangered Bagrid Catfish Pseudobagrus ichikawai

Ecology and Evolution, Volume 16, Issue 4, April 2026.
Using genome‐wide SNP data, we revealed previously undetected population structure in the endangered bagrid catfish Pseudobagrus ichikawai. Our results suggest that past paleo‐river systems shaped the current genetic connectivity across the Ise Bay area, while low genetic diversity indicates historical bottlenecks and recent inbreeding.
Keisuke Onuki, Ryoichi Tabata, Tappei Mishina, Mutsumi Nishida, Katsutoshi Watanabe   +4 more
wiley   +1 more source

A BRIEF ANALYSIS OF THE PUBLIC INSTITUTIONS BUGET: THEORETICAL AND PRACTICAL APPROACHES

Studia Universitatis Babeş-Bolyai Negotia, 2018
In this paper, we will mainly focus on the new budgetary tendencies of the Public Institutions, financed entirely or partially from the state budget, in the desire to highlight the newest aspects found at the level of the activities carried out in the ...
Ana Monica POP
doaj   +1 more source

Higher Genetic Diversity Across Several Small Patches Compared to a Single Large Patch: A Within‐Species Test of SLOSS

Evolutionary Applications, Volume 19, Issue 3, March 2026.
ABSTRACT The SLOSS (Single Large or Several Small) debate is crucial in reserve design, focusing on evaluating the conservation efficacy of a single large reserve versus multiple small reserves for species preservation. While accumulating evidence suggests that multiple small reserves may conserve greater species diversity, the question of how to ...
Fumin Lei, Dandan Li, Hua Zhu, Yuzhu Xia, Xinyi Chen, Jianxiang Yu, Shuiliang Guo, Jing Yu   +7 more
wiley   +1 more source

Environmental restraint: A hidden risk factor for stress-induced depression in rats

IBRO Neuroscience Reports
Little is known about the impact of environmental restraint, characterized by limited space and a lack of stimulating elements, on adult mental and physical health.
Hiroko Mochizuki-Kawai, Seita Nakazawa, Hideaki Oike, Hiromi Kimoto, Satoru Tomita, Michimasa Toyoshima, Tingbi Xiong, Kazuo Yamada   +7 more
doaj   +1 more source

Combining ability and heterosis in partial resistance to gray leaf spot in elite maize (Zea mays L.) genotypes

Crop Science, Volume 66, Issue 1, January/February 2026.
Abstract Six sets of 48 maize (Zea mays L.) inbred lines, and their 96 single crosses generated using the North Carolina Mating Design II system, were evaluated for resistance to gray leaf spot (GLS). The aim of the study was to assess the implications of combining ability, heterotic effects, and potence ratio in breeding for GLS resistance in maize ...
James O. Nyanapah, Patrick. O. Ayiecho, Julius O. Nyabundi, Washington Otieno, Peter S. Ojiambo   +4 more
wiley   +1 more source

Italy's state budget

PSL Quarterly Review, 2014
The article analyses the development of the Italian financial situation in the first three years of this post-war period. After some introductory remarks illustrating the structure of the Italian budget, the author compares the original estimates ...
G.E.M. G.E.M.
doaj   +1 more source

Design and characterization of calprotectin tetramerization variants for probing the role of oligomerization in receptor activation

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Calprotectin is a heterodimer of the S100A8 and S100A9 EF‐hand calcium binding proteins, which activates cell surface receptors that signal through the NF‐κB inflammatory signaling pathway. Like all S100 proteins, calcium‐induced conformational changes in calprotectin are required for binding to partner proteins.
Velia Garcia, Areetha D'Souza, Natalia Kozlyuk, Yasiru R. Perera, Steven M. Damo, Walter J. Chazin   +5 more
wiley   +1 more source

Clinical Validation of Digital PCR for Precise m.3243A>G Heteroplasmy Quantification in Early‐Onset Diabetes

Journal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Mitochondrial DNA m.3243A>G variant causes maternally inherited diabetes with deafness. We developed a droplet digital PCR (dPCR) assay to quantify m.3243A>G heteroplasmy and investigated its prevalence in Chinese Han early‐onset diabetes patients.
Xiaomu Kong, Lei Bei, Peng Gao, Lixia Lu, Haoyan Zhu, Yongwei Jiang, Meimei Zhao, Yi Liu, Guozhen Wang, Mo Li, Ziyi Feng, Guoxiong Deng, Yongtong Cao, Liang Ma, Hannah Wesley   +14 more
wiley   +1 more source