Results 1 to 10 of about 53,251 (245)

Engineered Lactococcus lactis secreting Flt3L and OX40 ligand for in situ vaccination-based cancer immunotherapy

open access: yesNature Communications, 2022
The probiotic Lactococcus lactis has been used for the delivery of therapeutic molecules. Here the authors engineer Lactococcus lactis to express a fusion protein of Flt3L and OX40 ligand, eliciting anti-tumor immune response in preclinical cancer models.
Junmeng Zhu   +13 more
doaj   +2 more sources

Whole-genome sequence analysis and probiotic characteristics of Lactococcus lactis Subsp. lactis strain Lac3 isolated from traditional fermented buffalo milk (Dadih)

open access: yesJournal of Genetic Engineering and Biotechnology, 2023
Background Probiotics are live microorganisms that provide beneficial effects on the host’s health when exploited in adequate amounts. This study aimed at carrying out whole-genome sequence analysis and in vitro potential probiotic characteristics of ...
Nshimiyimana Sylvere   +5 more
doaj   +2 more sources

The Lactococcus lactis Pan-Plasmidome [PDF]

open access: yesFrontiers in Microbiology, 2019
Plasmids are autonomous, self-replicating, extrachromosomal genetic elements that are typically not essential for growth of their host. They may encode metabolic capabilities, which promote the maintenance of these genetic elements, and may allow ...
P. Kelleher   +5 more
semanticscholar   +7 more sources

Immunomodulatory Activity of Lactococcus lactis GCWB1176 in Cyclophosphamide-Induced Immunosuppression Model

open access: yesMicroorganisms, 2020
Recently, Lactococcus lactis subsp. lactis has been reported to have immunostimulating properties in an immunosuppressed-animal model. However, the immunological activities of Lactococcus lactis and the molecular mechanisms remain unclear. In this report,
Yong Pil Hwang, , Hye GWANG Jeong
exaly   +2 more sources

Physical and Antibacterial Properties of Sodium Alginate—Sodium Carboxymethylcellulose Films Containing Lactococcus lactis

open access: yesMolecules, 2018
Edible films have gradually become a research focus for food packaging materials due to a variety of benefits, including environmental friendliness, good barrier properties, and good carrying capacity.
Jingsong Ye   +3 more
doaj   +2 more sources

From Genome to Phenotype: An Integrative Approach to Evaluate the Biodiversity of Lactococcus lactis

open access: yesMicroorganisms, 2017
Lactococcus lactis is one of the most extensively used lactic acid bacteria for the manufacture of dairy products. Exploring the biodiversity of L. lactis is extremely promising both to acquire new knowledge and for food and health-driven applications. L.
Marie-Line Daveran-Mingot   +2 more
exaly   +3 more sources

Lactococcus lactis As a Versatile Vehicle for Tolerogenic Immunotherapy

open access: yesFrontiers in Immunology, 2018
Genetically modified Lactococcus lactis bacteria have been engineered as a tool to deliver bioactive proteins to mucosal tissues as a means to exert both local and systemic effects.
Chantal Mathieu   +2 more
exaly   +2 more sources

Conversion of methionine to methional byLactococcus lactis [PDF]

open access: yesFEMS Microbiology Letters, 2001
Lactic acid bacteria were screened for methional production from 4-methylthio-2-ketobutanoate. Only Lactococcus lactis IFPL730 produced high amounts of methional. It was demonstrated that production of this compound was an exclusively enzymatic reaction. The present work describes for the first time that L.
Carmen Peláez   +2 more
exaly   +4 more sources

Metabiotics - development of probiotic concept [PDF]

open access: yesТехнологія виробництва і переробки продуктів тваринництва, 2022
The urgency of development of technology of synbiotic dairy products with metabolites on the basis of microbial consortia of probiotic bacteria is substantiated in the article.
Kryzhak L., Kalinina H.
doaj   +1 more source

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