Results 141 to 150 of about 3,267 (182)

TP53-mutated myelodysplastic syndromes and acute myeloid leukemia: a comprehensive overview of targeted approaches. [PDF]

Front Oncol
Deshpande S, Li WF, Song J, Forsberg M, Cerchione C, Martinelli G, Konopleva M.   +6 more
europepmc   +1 more source

Chemical Constituents Comparison Between the Flowers of <i>Sophora japonica</i> L. and <i>Robinia pseudoacacia</i> L. by UPLC-Q-TOF-MS/MS and HPLC. [PDF]

Molecules
Sun CC, Chen YT, Xu HX, Guo YX, Zhang QF.   +4 more
europepmc   +1 more source

UHPLC-Q-Orbitrap-HRMS-Based Multilayer Mapping of the Pharmacodynamic Substance Basis and Mechanistic Landscape of Maizibizi Wan in Chronic Nonbacterial Prostatitis Therapy. [PDF]

Pharmaceuticals (Basel)
Maihemuti M, Nuermaimaiti M, Maimaitiming W, Paierhati A, Ji H, Abduwaki M, Yang X, Mohammadtursun N.   +7 more
europepmc   +1 more source

Crystallographic and DFT study of novel dimethoxybenzene derivatives. [PDF]

BMC Chem
Elewa NN, Mabied AF.
europepmc   +1 more source

Enhancing Nonylphenol Biodegradation: The Role of Acetyl-CoA C-Acetyltransferase in <i>Bacillus cereus</i>. [PDF]

BioTech (Basel)
Lu F, Luo D, Yang L, Dong R.
europepmc   +1 more source

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation. [PDF]

Nat Commun
Roychowdhury T, McNutt SW, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, De Stanchina E, Corben A, Modi S, Alpaugh ML, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F.   +31 more
europepmc   +1 more source

KA h71: 7/1

Höjer, Peter
core  

Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71 [PDF]

Journal of Labelled Compounds and Radiopharmaceuticals, 2016
Heat shock protein 90 (Hsp90) is an ATP dependent molecular chaperone protein whose function is critical for maintaining several key proteins involved in survival and proliferation of cancer cells. PU-H71 (1), is a potent purine-scaffold based ATP pocket
Jason S. Lewis, Nagavarakishore Pillarsetty, Mark P Dunphy   +2 more
exaly   +4 more sources

The novel HSP90 inhibitor, PU-H71, suppresses glial cell activation but weakly affects clinical signs of EAE [PDF]

Journal of Neuroimmunology, 2013
Ansamycins are very effective HSP90 inhibitors that showed significant beneficial effects in the treatment of EAE. However, their toxicity and poor stability in solution limit their clinical use.
Cinzia Dello Russo, Pierluigi Navarra, Gabriela Chiosis   +2 more
exaly   +4 more sources