Results 21 to 30 of about 9,993 (172)
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
, 2018 Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
core +1 more source
Israel Journal of Chemistry, Volume 63, Issue 5-6, June 2023., 2023 Abstract Staphylococcus aureus is a ubiquitous bacterium that has become a major threat to human health due to its extensive toxin production and tremendous capacity for antibiotic resistance (e. g., MRSA “superbug” infections). Amid a worsening antibiotic resistance crisis, new strategies to combat this deadly microbe that remove the selective ...
Thomas J. Polaske +5 more
wiley +1 more source
The small GTPase Sar1, control centre of COPII trafficking
FEBS Letters, Volume 597, Issue 6, Page 865-882, March 2023., 2023 Newly synthesised secretory proteins are transported from the endoplasmic reticulum towards the Golgi apparatus in COPII‐coated vesicles. COPII vesicle budding starts with the activation of a small GTPase, Sar1. Here, we review the literature on Sar1 focussing on its role in the recruitment of the COPII coat and in membrane remodelling, and on the ...
Sander E. Van der Verren, Giulia Zanetti
wiley +1 more source
Efectos de la descentralización sobre la acumulación de infraestructura pública: el caso de España
El Trimestre Económico, 2018 Antecedentes: España es un país altamente descentralizado. Recientemente, el debate sobre la descentralización se ha visto reforzado por la reclamación de independencia liderada por las autoridades del gobierno de Cataluña.
Henry Aray
doaj +1 more source
Horizontal Fiscal Imbalance In The United States
Folia Oeconomica Stetinensia, 2014 Regional inequalities are currently a challenge for the majority of countries, in particular large ones, certain of which are federations. The federal state system is more complex than the unitary system. This results in specific problems. One of them is
Kowalik Paweł
doaj +1 more source
Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
, 2010 Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source
El Trimestre Económico, 2019 Antecedentes: La segunda generación de modelos de federalismo fiscal (SGFF) advierte que la dependencia fiscal puede incitar la pereza de los gobiernos locales y estancar la generación de ingresos propios; además, puede promover la corrupción y una menor
Alfonso Mendoza Velázquez
doaj +1 more source
Complete replication of hepatitis C virus in cell culture. [PDF]
, 2005 Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research progress on this important human pathogen.
Burton, Dennis R +10 more
core +1 more source
Fiscal federalism and a separate budget for the euro area
International Journal of Management and Economics, 2018 The core objective of this paper is to determine the main political and economic conditions and challenges related to the possible evolution of the integration process in the euro area toward fiscal federalism and fiscal union as a way to increase the ...
Oręziak Leokadia
doaj +1 more source
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
, 2009 Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources