Results 51 to 60 of about 9,993 (172)

First identification of a recombinant form of hepatitis C virus in Austrian patients by full-genome next generation sequencing. [PDF]

PLoS ONE, 2017
Hepatitis C virus (HCV) intergenotypic recombinant forms have been reported for various HCV genotypes/subtypes in several countries worldwide. In a recent study, four patients living in Austria had been identified to be possibly infected with a ...
Evelyn Stelzl, Bernhard Haas, Bernd Bauer, Sherry Zhang, Ellen H Fiss, Grantland Hillman, Aaron T Hamilton, Rochak Mehta, Marintha L Heil, Ed G Marins, Brigitte I Santner, Harald H Kessler   +11 more
doaj   +1 more source

Hepatitis C Virus Saint Petersburg Variant Detection With Machine Learning Methods

Journal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT Hepatitis C virus infection is a significant global health concern, affecting millions worldwide. Although direct‐acting antivirals achieve over 90% success rate, treatment failures still occur, particularly when pan‐genotypic DAAs are unavailable, and drugs need to be chosen based on the present HCV genotype.
Nurhan Arslan, Bernhard Reuter, Joachim Buech, Thomas Lengauer, Martin Obermeier, Rolf Kaiser, Nico Pfeifer   +6 more
wiley   +1 more source

Harmonizing the complexities of financial development and fiscal decentralization in highly populated nations for monitoring environmental quality

Heliyon
The increasing challenges posed by global warming underscore the need to examine the contributing factors comprehensively. This study explores the complex interaction that enhances the financial autonomy of local governments (fiscal decentralization ...
Yi Ding, Fayaz Hussain Tunio, Agha Amad Nabi   +2 more
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B., Dong, C., Dong, H., Elliott, R., Li, P.   +4 more
core   +1 more source

Transcript and Lipid Profile Alterations in Astrocyte‐Neuron Mitochondrial Transfer Under Lipopolysaccharide Exposure: An In Vitro Study

Journal of Neurochemistry, Volume 169, Issue 2, February 2025.
The astrocyte‐conditioned medium (ACM) was obtained by incubating astrocytes with LPS (1 μg/mL) for 24 h. After removing cellular debris, the mitochondria‐depleted astrocyte‐conditioned medium (mdACM) was produced by filtering out mitochondria from ACM using a 0.2‐μm filter.
Yufei Kan, Hong Wang, Huaying Lin, Yongfa Li, Shuaijie Pei, Yan Cui, Keliang Xie, Hongguang Chen, Yonghao Yu   +8 more
wiley   +1 more source

GmDRR1, a dirigent protein resistant to Phytophthora sojae in Glycine max (L.) Merr.

Journal of Integrative Agriculture, 2018
Soil-borne pathogen Phytophthora sojae is an oomycete that causes devastating damage to soybean yield. To mine original resistant genes in soybean is an effective and environmentally-friend approach controlling the disease.
Qing-shan CHEN, Guo-long YU, Jia-nan ZOU, Jing WANG, Hong-mei QIU, Rong-sheng ZHU, Hui-lin CHANG, Hong-wei JIANG, Zhen-bang HU, Chang-yu LI, Yan-jiao ZHANG, Jin-hui WANG, Xue-ding WANG, Shan GAO, Chun-yan LIU, Zhao-ming QI, Yong-fu FU, Da-wei XIN   +17 more
doaj   +1 more source

Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus

Advanced Science, Volume 12, Issue 3, January 20, 2025.
A unique role of vimentin in orchestrating HCV cell–cell transmission is characterized, by specifically interacting with HCV structural protein E1 through the head domain of vimentin. It is further proved that vimentin functions through its cell surface form and vimentin antibody exerted a pronounced inhibitory effect on the cell–cell transmission of ...
Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu   +6 more
wiley   +1 more source

A library of infectious hepatitis C viruses with engineered mutations in the E2 gene reveals growth-adaptive mutations that modulate interactions with scavenger receptor class B type I [PDF]

, 2016
While natural hepatitis C virus (HCV) infection results in highly diverse quasispecies of related viruses over time, mutations accumulate more slowly in tissue culture, in part because of the inefficiency of replication in cells.
Chen, Kevin, Diamond, Michael S, Evans, Matthew J, Fremont, Daved H, Luca, Vincent C, Schwarz, Megan C, Wang, David, White, James P, Zuiani, Adam   +8 more
core   +2 more sources

Fuel Consumption Prediction in Regional Transport Based on Selected Bus Line Characteristics

Journal of Advanced Transportation, Volume 2025, Issue 1, 2025.
From an operational, economic and environmental point of view, it is crucial for public transport authorities and operators to be able to estimate fuel consumption in suburban bus transport. This is especially important when planning a new bus line or re‐routing an existing one. This paper aims to identify a simple model for predicting fuel consumption
Tomáš Skrúcaný, Bibiána Poliaková, Martin Kendra, Oľga Blažeková, Mária Vojteková, Jing Zhao   +5 more
wiley   +1 more source

Economic growth target fluctuation and bond issuance by LGFVs

International Review of Economics & Finance
This paper examines the impact of China's economic growth target management system on local government debt. Specifically, it examines how economic growth target fluctuation affects bond issuance by LGFVs from the perspective of economic uncertainty ...
Shulin Liu, Xianbin Wang, Liangxiong Huang   +2 more
doaj   +1 more source