Results 71 to 80 of about 3,728 (189)

Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR

open access: yesScientific Reports, 2019
The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who ...
Lorena Vigón   +14 more
doaj   +1 more source

Sustainability of state government debts in Brazil [PDF]

open access: yesEconomiA
PurposeThis paper evaluates the sustainability of subnational government debts in Brazil, with a focus on how borrowing costs compared to revenue growth and how fiscal policy contributed to debt dynamics from 2007 to 2022.Design/methodology/approachThe ...
Felipe Soares Luduvice   +1 more
doaj   +1 more source

Analysis of immune responsiveness versus physical properties of HCV polyprotein.

open access: yes, 2013
A) Antibody response (RF) scores plotted along the length of the HCV H77 polyprotein, B) T cell response frequency (RF) scores plotted along the length of the HCV H77 polyprotein, C) Hydrophilicty data calculated for the HCV H77 polyprotein using the ...
Kerrie Vaughan (19116)   +5 more
core   +1 more source

Mapping Determinants of Hepatitis C Virus E1/E2 Transmembrane Interactions Using Intergenotypic Chimeras

open access: yesViruses
Hepatitis C virus (HCV) infection remains a major global health burden, and no vaccine preventing chronic infection is available. The envelope glycoproteins, E1 and E2, form a complex essential for viral entry; however, the mechanisms governing E1/E2 ...
Margherita Fanalista   +4 more
doaj   +1 more source

An E2 BLd-derived peptide inhibits HCV infection.

open access: yes, 2018
(A) Putative BL movements that can modulate E2 rearrangements within E1E2 heterodimers. Rotation angles of the E2core structure are indicated (Reference: Fig 3B) and illustrated by a black cross harboring 4 color extremities. (B) Schematic representation
Linda Dib (124223)   +19 more
core   +1 more source

Characterization of pearl millet hybrids and their parental lines by seed storage protein markers

open access: yesElectronic Journal of Plant Breeding, 2017
The variability of seed storage-proteins of 21 pearl millet genotypes were analyzed by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE).
A. Manivannan
doaj   +1 more source

Genotype-specific trans-complementation of the NS2 S168A-mediated defect in infectious virus production.

open access: yes, 2013
(A) Extracellular virus yields (FFU/ml) determined three days after transfection of JFH1 RNA, with or without the S168A mutation (“SA”), into normal FT3-7 cells or VEE replicon cells expressing GFP, Flag-JFH1-NS2, Flag-JFH1-NS2/SA, or Flag-H77-NS2.
Yinghong Ma (373014)   +3 more
core   +1 more source

E2 ectodomain models.

open access: yes, 2020
Partial crystal structures were used as the basis for building full length models of the E2 ectodomain (defined here as residues 384–645 of the HCV polyprotein). A. PDB 4MWF partial structure of H77 E2. B.
Machaela Palor (8506497)   +6 more
core   +1 more source

Analyzing the impact of synergistic environmental regulations and local government competition on carbon neutrality goals

open access: yesJournal of Innovation & Knowledge
Integration and synergy of environmental policies is crucial for maximizing carbon reduction effects. This study investigates the heterogeneous impact of environmental policy synergy on carbon neutrality using panel data from 30 Chinese provinces between
Jun Zhao, Lelai Shi
doaj   +1 more source

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