Results 51 to 60 of about 3,728 (189)

Amino acid alignment of all our HCV sequences in comparison with the HCV prototype strain H77 indicating conserved amino acid positions (with red dots) and variable sites (letters).

, 2019
Amino acid alignment of all our HCV sequences in comparison with the HCV prototype strain H77 indicating conserved amino acid positions (with red dots) and variable sites (letters).
David O. Olaleye (4789512), Juliet A. Shenge (6307943), Georgina N. Odaibo (4789518)   +2 more
core   +1 more source

Hepatitis C Virus Saint Petersburg Variant Detection With Machine Learning Methods

Journal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT Hepatitis C virus infection is a significant global health concern, affecting millions worldwide. Although direct‐acting antivirals achieve over 90% success rate, treatment failures still occur, particularly when pan‐genotypic DAAs are unavailable, and drugs need to be chosen based on the present HCV genotype.
Nurhan Arslan, Bernhard Reuter, Joachim Buech, Thomas Lengauer, Martin Obermeier, Rolf Kaiser, Nico Pfeifer   +6 more
wiley   +1 more source

H77/JFH1_ΔHVR1 escaped from HMAb AR5A antibody neutralization.

, 2017
(A) Huh7.5 cells were infected with H77/JFH1ΔHVR1 and treated with 5 μg/ml of AR5A antibody during the indicated period of time. Treatment I, II, III were treated independently and cultured along with the untreated control.
Mansun Law (320712), Jens Bukh (162343), Rodrigo Velázquez-Moctezuma (3776023), Jannick Prentoe (162323)   +3 more
core   +1 more source

GmDRR1, a dirigent protein resistant to Phytophthora sojae in Glycine max (L.) Merr.

Journal of Integrative Agriculture, 2018
Soil-borne pathogen Phytophthora sojae is an oomycete that causes devastating damage to soybean yield. To mine original resistant genes in soybean is an effective and environmentally-friend approach controlling the disease.
Qing-shan CHEN, Guo-long YU, Jia-nan ZOU, Jing WANG, Hong-mei QIU, Rong-sheng ZHU, Hui-lin CHANG, Hong-wei JIANG, Zhen-bang HU, Chang-yu LI, Yan-jiao ZHANG, Jin-hui WANG, Xue-ding WANG, Shan GAO, Chun-yan LIU, Zhao-ming QI, Yong-fu FU, Da-wei XIN   +17 more
doaj   +1 more source

Isolation and characterization of highly replicable hepatitis C virus genotype 1a strain HCV-RMT. [PDF]

PLoS ONE, 2013
Multiple genotype 1a clones have been reported, including the very first hepatitis C virus (HCV) clone called H77. The replication ability of some of these clones has been confirmed in vitro and in vivo, although this ability is somehow compromised.
Masaaki Arai, Yuko Tokunaga, Asako Takagi, Yoshimi Tobita, Yuichi Hirata, Yuji Ishida, Chise Tateno, Michinori Kohara   +7 more
doaj   +1 more source

Transcript and Lipid Profile Alterations in Astrocyte‐Neuron Mitochondrial Transfer Under Lipopolysaccharide Exposure: An In Vitro Study

Journal of Neurochemistry, Volume 169, Issue 2, February 2025.
The astrocyte‐conditioned medium (ACM) was obtained by incubating astrocytes with LPS (1 μg/mL) for 24 h. After removing cellular debris, the mitochondria‐depleted astrocyte‐conditioned medium (mdACM) was produced by filtering out mitochondria from ACM using a 0.2‐μm filter.
Yufei Kan, Hong Wang, Huaying Lin, Yongfa Li, Shuaijie Pei, Yan Cui, Keliang Xie, Hongguang Chen, Yonghao Yu   +8 more
wiley   +1 more source

THE ASIAN TIGERS’ DEGREE OF PARTICIPATION IN THE NEW SILK ROADS INITIATED BY CHINA [PDF]

Global Economic Observer
The primary objective of this paper is to synthesize the positions of nine key actors relevant to the world economy, specifically the Asian Tigers, regarding China and its Belt and Road Initiative (BRI).
IULIA MONICA OEHLER-ŞINCAI, PhD
doaj  

The evolution of Brasília spatial structure from 1975 to 2015

Journal of Urban Management
Planned cities remain underexplored in the empirical literature on urban spatial structure, particularly from a long-term perspective using high-resolution data. This paper addresses this gap by analyzing how a highly regulated, purpose-built capital has
Lucas Dutra de Paulo, Ricardo Carvalho de Andrade Lima   +1 more
doaj   +1 more source

The Risk of GLP‐1 Receptor Agonist (GLP‐1 RA) Exposure in Early Pregnancy. A Call to Action: Quantifying the Impact on Pregnancy Outcomes in the United Kingdom

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6455-6457, July 2026.
Michael Stedman, Pensee Wu, Ian Halsall, Nadia Chaudhury, Barbara McGowan, Martin B. Whyte, Akheel Syed, Adrian Heald   +7 more
wiley   +1 more source

Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus

Advanced Science, Volume 12, Issue 3, January 20, 2025.
A unique role of vimentin in orchestrating HCV cell–cell transmission is characterized, by specifically interacting with HCV structural protein E1 through the head domain of vimentin. It is further proved that vimentin functions through its cell surface form and vimentin antibody exerted a pronounced inhibitory effect on the cell–cell transmission of ...
Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu   +6 more
wiley   +1 more source