Results 11 to 20 of about 6,737 (128)

Extracellular Vesicular Delta-Like Ligand 3 and Subtype Transcription Factors for Small Cell Lung Cancer Diagnosis. [PDF]

Adv Sci (Weinh)
Small cell lung cancer (SCLC) harbors high molecular heterogeneity. Using a new liquid biopsy assay, SCLC subtypes can be identified by measuring mRNA of subtype transcription factors (ASCL1, POU2F3, and NEUROD1) in exosome‐rich extracellular vesicles. Combining with Delta‐like ligand 3 (DLL3) mRNA in exosomes and its membrane protein in extracellular ...
Li H, Chiang CL, Kwak KJ, Lee HL, Wang X, Romano G, Saviana M, Toft R, Cheng TS, Chang Y, Hsiang BD, Liu GW, Mo X, Ma Y, Pan J, Rima XY, Kim TN, Reategui E, Shen CN, Chu YS, Croce C, Chang PM, Yeh YC, Carbone DP, Huang CF, Chiang CL, Nana-Sinkam P, Lee LJ.   +27 more
europepmc   +2 more sources

The HI Content of Compact Groups of Galaxies [PDF]

, 2004
The HI content of Hickson Compact Groups in the southern hemisphere is measured using data from the HI Parkes All Sky Survey (HIPASS), and dedicated observations using the narrowband filter on the Multibeam instrument on the Parkes telescope.
Barnes, Braun, Chamaraux, Chamaraux, D. G. Barnes, D. J. Pisano, de Vaucouleurs, Hickson, Huchtmeier, Huchtmeier, J. B. Stevens, Karachentseva, Leon, M. J. Drinkwater, Nilson, R. L. Webster, Sandage, Verdes-Montenegro   +17 more
core   +2 more sources

Adenosinium 3,5-dinitrosalicylate [PDF]

, 2004
The crystal structure of adenosinium 3,5-dinitrosalicylicate, C10H14N5O4+烷H3N2O7-, shows the presence of a primary chain structure formed through homomeric head-to-tail cyclic R22(10) hydrogen-bonding interactions between hydroxy O- and both purine and ...
Healy, Peter, Smith, Graham, Wermuth, Urs   +2 more
core   +2 more sources

Selective M3 Muscarinic Receptor Antagonist Inhibits Small-Cell Lung Carcinoma Growth in a Mouse Orthotopic Xenograft Model

Journal of Pharmacological Sciences, 2011
.: In small cell lung carcinoma (SCLC), acetylcholine (ACh) is synthesized and secreted, and it acts as an autocrine growth factor through activation of its receptors, muscarinic receptor (mAChR) and nicotinic receptor (nAChR). Alteration of tumor growth
Nozomi Ami, Kazumi Koga, Hiroshi Fushiki, Yoko Ueno, Yoshio Ogino, Hisashi Ohta   +5 more
doaj   +1 more source

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy [PDF]

, 2017
BCL-2 family proteins are central regulators of mitochondrial apoptosis and validated anti-cancer targets. Using small cell lung cancer (SCLC) as a model, we demonstrated the presence of differential addiction of cancer cells to anti-apoptotic BCL-2, BCL-
Chen, Hui-Chen, Cheng, Emily H, Dong, Yiyu, Ganesan, Yogesh Tengarai, Han, Song, Hellmann, Matthew D, Hsieh, James J, Inoue-Yamauchi, Akane, Ishizawa, Kota, Jebiwott, Sylvia, Jeng, Paul S, Kim, Kwanghee, Kris, Mark G, Pietanza, Maria C   +13 more
core   +2 more sources

Use of Investment Areas in Special Economic Zones in Poland in the Context of Planned Legislation Changes

Real Estate Management and Valuation, 2019
Boundaries of Special Economic Zones (SEZs) in Poland change constantly and preferential conditions, including attractive investment land sites, become important factors underlining a decision to choose the location of an enterprise.
Lizińska Wiesława
doaj   +1 more source

Preliminary interpretation of Titan plasma interaction as observed by the Cassini Plasma Spectrometer: Comparisons with Voyager 1 [PDF]

, 2006
The Cassini Plasma Spectrometer (CAPS) instrument observed the plasma environment at Titan during the Cassini orbiter's TA encounter on October 26, 2004.
Andre, N, Berthelier, JJ, Bolton, S, Coates, AJ, Crary, F, Hartle, RE, Johnson, RE, McComas, DJ, Neubauer, FM, Reisenfeld, D, Rymer, A, Simpson, D, Sittler, EC, Smith, HT, Steinberg, JT, Szego, K, Vilppola, J, Young, DT   +17 more
core   +1 more source

Monitoring and Determining Mitochondrial Network Parameters in Live Lung Cancer Cells. [PDF]

, 2019
Mitochondria are dynamic organelles that constantly fuse and divide, forming dynamic tubular networks. Abnormalities in mitochondrial dynamics and morphology are linked to diverse pathological states, including cancer.
Achuthan, Srisairam, Armstrong, Brian, Batra, Surinder K, Chu, Peiguo G, Kulkarni, Prakash, Lennon, Frances, Li, Haiqing, Mambetsariev, Isa, Mirzapoiazova, Tamara, Nasser, Mohd W, Nathan, Anusha, Salgia, Ravi, Srivstava, Saumya   +12 more
core   +1 more source

O-GalNAc Glycosylation Activates MBL-Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis. [PDF]

Adv Sci (Weinh)
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Chen X, Bao W, Liu K, Jing N, Du G, Jiang L, You Q, Zhang Y, Xu P, Cheng C, Wang N, Xi X, Wang M, Liu Y, Wang J, Zhao H, Zhang S, Wu D, Ng CF, Pan J, Xue W, Gao WQ, Zhang P, Zhang K, Zhu HH.   +24 more
europepmc   +2 more sources

Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model

BMC Cancer, 2010
Background Angiogenesis is the formation of neovasculature from a pre-existing vascular network. Progression of solid tumors including lung cancer is angiogenesis-dependent.
Watkins D Neil, Hammers Hans, Tang Benjamin C, Karagiannis Emmanouil D, Koskimaki Jacob E, Pili Roberto, Popel Aleksander S   +6 more
doaj   +1 more source