Results 21 to 30 of about 6,737 (128)

Rapid Cancer Fluorescence Imaging Using A γ-Glutamyltranspeptidase-Specific Probe For Primary Lung Cancer

Translational Oncology, 2016
BACKGROUND: We set out to examine the activity of γ-glutamyltranspeptidase (GGT) in lung cancer and the validity of γ-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) for intraoperative imaging of primary lung cancer.
Haruaki Hino, Mako Kamiya, Kentaro Kitano, Kazue Mizuno, Sayaka Tanaka, Nobuhiro Nishiyama, Kazunori Kataoka, Yasuteru Urano, Jun Nakajima   +8 more
doaj   +1 more source

Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis. [PDF]

, 2013
Synthesis of acetylcholine (ACh) by non-neuronal cells is now well established and plays diverse physiologic roles. In neurons, the Na(+) -dependent, high affinity choline transporter (CHT1) is absolutely required for ACh synthesis. In contrast, some non-
Campling, M.D., FRCPC, Barbara, Dissen, Gregory A, Lindstrom, Jon, Rekow, Stephen S, Sekhon, Harmanjatinder S, Singleton, Corey-Ayne, Song, Pingfang, Spindel, Eliot R, Zhou, Minerva   +8 more
core   +1 more source

An atlas of 2.4 to 4.1 microns ISO/SWS spectra of early-type stars [PDF]

, 2002
We present an atlas of spectra of O- and B-type stars, obtained with the Short Wavelength Spectrometer (SWS) during the Post-Helium program of the Infrared Space Observatory (ISO).
A. de Koter, A. Lenorzer, B. Vandenbussche, Bjorkman, Buscombe, Churchwell, Conti, Coté, Coté, Dachs, de Graauw, de Koter, Dougherty, Gies, Guetter, Hanson, Hanson, Hiltner, Hony, Humphreys, Johnson, Kaper, Kaufer, Kessler, Kudritzki, Kudritzki, L. B. F. M. Waters, L. Kaper, Lamers, Lamers, Lennon, Lesh, Levato, Massey, Meyer, Morgan, Morgan, Morris, Morris, Morris, Morris, Mountain, Najarro, P. Morris, Poeckert, Puls, S. Hony, Smith, T. R. Geballe, Telting, van der Hucht, van Paradijs, Vandenbussche, Walborn, Walborn, Walborn, Wallace, Waters, Waters, Zorec   +59 more
core   +4 more sources

IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells

Journal of Experimental & Clinical Cancer Research, 2017
Background Recently, immunotherapy with anti-PD-1 antibodies has shown clinical benefit in recurrent Small Cell Lung Cancer (SCLC). Since anti-PD-1 re-activates anti-tumor Cytotoxic T Lymphocyte (CTL) responses, it is crucial to understand the mechanisms
Grazia Carbotti, Amin Reza Nikpoor, Paola Vacca, Rosaria Gangemi, Chiara Giordano, Francesco Campelli, Silvano Ferrini, Marina Fabbi   +7 more
doaj   +1 more source

Production of Charmed Tetraquarks from $B_c$ and $B$ decays

, 2016
Hadronic states composed of multi-quark flavors may exist in reality since they are not prohibited by QCD. Compact four quark systems of color singlet are classified as tetraquarks.
He, Xiao-Gang, Wang, Wei, Zhu, Rui-Lin
core   +1 more source

Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming [PDF]

, 2017
Components of the SWI/SNF chromatin remodeling complex, including BRG1 (also SMARCA4), are inactivated in cancer. Among other functions, SWI/SNF orchestrates the response to retinoid acid (RA) and glucocorticoids (GC) involving downregulation of MYC. The
Condom i Mundó, Enric, Esteller, Manel, Gomez, A., Moran, Sebastian, Romero, Octavio A., Sánchez Céspedes, Montserrat, Torres-Diz, M., Verdura, S., Villanueva Garatachea, Alberto   +8 more
core   +1 more source

Small Cell Lung Cancer Establishes a Metabolic Autocrine Mechanism Through Active Extracellular ATP Transport

Cancer Science, EarlyView.
Small cell lung cancer (SCLC) actively exports ATP through PANX1 channels, triggering P2RX7‐mediated autocrine signaling and promoting tumor proliferation. Inhibition of PANX1 or P2RX7 disrupts this loop and suppresses tumor growth. ABSTRACT Small cell lung cancer (SCLC) is an aggressive malignancy with a 5‐year survival rate of less than 7%.
Takeshi Tsuruda, Manabu Kodama, Keiichi I. Nakayama   +2 more
wiley   +1 more source

A New Spin on Galactic Dust

, 2001
We present a new puzzle involving Galactic microwave emission and attempt to resolve it. On one hand, a cross-correlation analysis of the WHAM H-alpha map with the Tenerife 10 and 15 GHz maps shows that the well-known DIRBE correlated microwave emission ...
A. N. Lasenby, Aled W. Jones, Angelica de Oliveira‐Costa, Carlos M. Gutierrez, Davies R. D., Douglas P. Finkbeiner, Haslam C. G. T., L. M. Haffner, Max Tegmark, R. A. Watson, R. D. Davies, R. Rebolo, Reich P., Reich W., Ron J. Reynolds, S. L. Tufte   +15 more
core   +1 more source

Evaluating the accuracy of the EcoservR toolkit for fine‐resolution habitat mapping

Ecological Solutions and Evidence, Volume 7, Issue 2, April–June 2026.
Accurate habitat maps are essential for monitoring ecological change and supporting nature recovery planning. We evaluate the EcoservR rule‐based habitat mapping toolkit using field survey data from Merseyside and the North York Moors, validating classifications across the Joint Nature Conservation Committee (JNCC) Phase 1 hierarchy.
Sandra Angers‐Blondin, Colm Bowe, Luke Kinross Bentley, Alex Owusu Amoakoh, Joe Bellis, Lucy Dowdall, Noémie Bonnin, Stamatia Galata, Hannah Branwood, Andrew Clark, Chloe Bellamy, Hanna Partoft   +11 more
wiley   +1 more source

Crystal structure of γ-carbonic anhydrase from the polyextremophilic bacterium Aeribacillus pallidus

Molecules and Cells
: The polyextremophilic bacterium Aeribacillus pallidus produces a thermo- and alkali-stable γ-carbonic anhydrase (γ-apCA), a homotrimeric metalloenzyme containing a zinc ion in its active site that catalyzes the reversible hydration of carbon dioxide ...
Seung Hun Choi, Mi Sun Jin
doaj   +1 more source