Overcoming divalent cation sensitivity is not the only challenge for functional study of ABC transporters within polymer lipid particles. [PDF]
Hawkins OP +5 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells. [PDF]
Chen C +9 more
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
<i>PSMD6</i> as a biomarker for hepatocellular carcinoma: A comprehensive bioinformatics analysis and <i>in vitro</i> validation. [PDF]
Liu J, Wang T, Zhu Z.
europepmc +1 more source
Patterns of cytokine gene expression of naïve and memory T lymphocytes in vivo. [PDF]
Bailey, S. +3 more
core
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia +7 more
wiley +1 more source
NorQD AAA+ complex drives metal insertion by a twisting mechanism. [PDF]
Kahle M +5 more
europepmc +1 more source

