Results 1 to 10 of about 23,240 (200)
Rapid Action of Aldosterone on Protein Levels of Sodium-Hydrogen Exchangers and Protein Kinase C Beta Isoforms in Rat Kidney [PDF]
International Journal of Endocrinology, 2017 Previous in vitro studies demonstrated that aldosterone rapidly activates sodium-hydrogen exchangers 1 and 3 (NHE 1 and 3). In vitro investigations revealed that protein kinase C (PKC) regulates NHE properties. We previously demonstrated that aldosterone
Somchit Eiam-Ong +3 more
doaj +4 more sources
The Role of Plasma Membrane Sodium/Hydrogen Exchangers in Gastrointestinal Functions: Proliferation and Differentiation, Fluid/Electrolyte Transport and Barrier Integrity [PDF]
Frontiers in Physiology, 2022 The five plasma membrane Na+/H+ exchanger (NHE) isoforms in the gastrointestinal tract are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities, and physiological regulation.
Katerina Nikolovska +2 more
doaj +2 more sources
Empagliflozin and Renal Sodium-Hydrogen Exchange in Healthy Subjects [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2023 Abstract Context Sodium glucose co-transporter-2 inhibitors exert clinically relevant cardiorenal protection. Among several mechanisms, inhibition of sodium-hydrogen exchanger-3 (NHE3) in proximal renal tubules has been proposed in rodents.
Edoardo Biancalana +7 more
openalex +4 more sources
Sodium hydrogen exchangers contribute to arenavirus cell entry. [PDF]
J Virol, 2014 ABSTRACT Several arenaviruses, chiefly Lassa virus (LASV), cause hemorrhagic fever (HF) disease in humans and pose a great public health concern in the regions in which they are endemic. Moreover, evidence indicates that the worldwide-distributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a neglected human
Iwasaki M, Ngo N, de la Torre JC.
europepmc +4 more sources
A Glycine max sodium/hydrogen exchanger enhances salt tolerance through maintaining higher Na+ efflux rate and K+/Na+ ratio in Arabidopsis [PDF]
BMC Plant Biology, 2019 Background Soybean (Glycine max (L.)) is one the most important oil-yielding cash crops. However, the soybean production has been seriously restricted by salinization.
Tian-Jie Sun +6 more
doaj +2 more sources
PLoS ONE, 2022 Sodium-hydrogen exchangers (NHEs) tightly regulate intracellular pH (pHi), proliferation, migration and cell volume. Heterogeneity exists between pulmonary endothelial cells derived from different vascular segments, yet the activity and isoform ...
Dylan Adams +2 more
doaj +2 more sources
Frontiers in Plant Science, 2022 Alkaline soil has a high pH due to carbonate salts and usually causes more detrimental effects on crop growth than saline soil. Sodium hydrogen exchangers (NHXs) are pivotal regulators of cellular Na+/K+ and pH homeostasis, which is essential for salt ...
Ting Jin +8 more
doaj +1 more source
Cognitive Sequelae and Hippocampal Dysfunction in Chronic Kidney Disease following 5/6 Nephrectomy
Brain Sciences, 2022 Neurological disorders are prevalent in patients with chronic kidney disease (CKD). Vascular factors and uremic toxins are involved with cognitive impairment in CKD.
Yeon Hee Yu +8 more
doaj +1 more source
Sodium/hydrogen‐exchanger‐2 modulates colonocyte lineage differentiation [PDF]
Acta Physiologica, 2022 AbstractAimThe sodium/hydrogen exchanger 2 (NHE2) is an intestinal acid extruder with crypt‐predominant localization and unresolved physiological significance. Our aim was to decipher its role in colonic epithelial cell proliferation, differentiation and electrolyte transport.MethodsAlterations induced by NHE2‐deficiency were addressed in murine nhe2−/−
Katerina Nikolovska +9 more
openaire +2 more sources
Journal of Virus Eradication, 2022 Because of rapid emergence and circulation of the SARS-CoV-2 variants, especially Omicron which shows increased transmissibility and resistant to antibodies, there is an urgent need to develop novel therapeutic drugs to treat COVID-19.
Yukinori Endo +7 more
doaj +1 more source