Results 171 to 180 of about 19,177,864 (274)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Zn-flux-enabled synthesis of orthorhombic kagome YbFe<sub>6</sub>Ge<sub>6</sub>: Yb reduction and magnetic behavior.

open access: yesChem Commun (Camb)
Meduri R   +7 more
europepmc   +1 more source

A special prime divisor of the sequence: Ah+B, A(h+1)+B,…, A(h+k−1)+B

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
Safwan Akbik
doaj   +1 more source

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