Results 171 to 180 of about 1,861,445 (361)

The dust properties of bubble H II regions as seen byHerschel [PDF]

open access: bronze, 2012
L. D. Anderson   +12 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

IRAS 16475–4609: A Young Compact H II Region Sculpting its Molecular Environment

open access: yesThe Astronomical Journal
We present a near-infrared spectroscopic and imaging analysis of the star-forming region IRAS 16475−4609, based on TripleSpec/SOAR spectroscopy and NEWFIRM/CTIO imaging, complemented by archival radio and submillimeter data.
Felipe Navarete   +2 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

When H II Regions are Complicated [PDF]

open access: green, 2019
Sam Geen   +3 more
openalex  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

An Enigmatic PeVatron in an Area around H ii Region G35.6−0.5

open access: yesThe Astrophysical Journal
Identifying Galactic PeVatrons (PeV particle accelerators) from ultrahigh-energy (UHE, >100 TeV) γ -ray sources plays a crucial role in revealing the origin of Galactic cosmic rays.
Zhen Cao   +299 more
doaj   +1 more source

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