Results 181 to 190 of about 1,094,944 (319)

Integral field spectroscopy of a sample of nearby galaxies II. Properties of the H parallel to regions [PDF]

, 2012
S. F. Sánchez, F. F. Rosales Ortega, R. A. Marino, J. Iglésias-Páramo, J. M. Vı́lchez, R. C. Kennicutt, Á. I. Díaz, D. Mast, A. Monreal‐Ibero, R. García Benito, Joss Bland‐Hawthorn, E. Pérez, R. M. González Delgado, B. Husemann, Á. R. López-Sánchez, R. Cid Fernandes, C. Kehrig, C. J. Walcher, A. Gil de Paz, Simon Ellis   +19 more
openalex  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Structural evolution of the whole mitochondrial genome and phylogenetic inference in snakes (Squamata: Serpentes), including the undescribed mitogenome of the Brazilian endemic and critically endangered pitviper Bothrops insularis. [PDF]

Genet Mol Biol
Salles-Oliveira I, Patané JSL, Nishiyama-Júnior MY, Silva MJJ.   +3 more
europepmc   +1 more source

RE-ANALYSIS OF THE RADIO LUMINOSITY FUNCTION OF GALACTIC H II REGIONS [PDF]

, 2009
R. Paladini, G. DeZotti, A. Noriega‐Crespo, S. Carey   +3 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Tuina Alleviates Pain Associated with Lumbar Disc Herniation by Regulating Functional Connectivity Between Inferior Frontal Triangularis and Multiple Brain Networks: A Randomized Controlled fMRI Study. [PDF]

J Pain Res
Jiang C, Zhang H, Wu X, Huang L, Zhou X, Lin J, Chen L, Huang H, Chen S, Zhang J, Lin Z.   +10 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish. [PDF]

Proc Natl Acad Sci U S A
Jamadagni P, Dai Y, Liu Y, Weinschutz Mendes H, Pruitt A, Khan S, Yang L, Huang TC, Huang X, Deans PJM, Balafkan N, Zhao D, Xu G, Liu Y, Li N, Wu W, Fitzpatrick SE, Neelakantan U, Chen T, Szialta C, Jin DS, Lacadie CM, Umlauf S, Papademetris X, Surovtseva YV, Brennand KJ, Wang Z, Hoffman EJ.   +27 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Hbs and Rst adhesion molecules provide a regional code that regulates cell elimination during epithelial remodeling. [PDF]

iScience
Ferreira-Pinto M, Aguilar-Aragón M, Rhiner C, Moreno E.   +3 more
europepmc   +1 more source