Results 191 to 200 of about 4,605,994 (345)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

When H II Regions are Complicated [PDF]

, 2019
Sam Geen, E. Pellegrini, Rebekka Bieri, Ralf S. Klessen   +3 more
openalex  

Spatial Distribution of Dust Grains within HiiRegions [PDF]

, 2002
Akio K Inoue
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Paused RNA polymerase primes promoters via RNA-mediated stabilisation of transcription factor ERα. [PDF]

Nat Commun
Mann R, Soota D, Das A, Podh NK, Mehta G, Notani D.   +5 more
europepmc   +1 more source

Topology and sizes of H ii regions during cosmic reionization [PDF]

, 2011
Martina M. Friedrich, Garrelt Mellema, Marcelo A. Alvarez, Paul R. Shapiro, Ilian T. Iliev   +4 more
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

H3K4me3 amplifies transcription at intergenic active regulatory elements. [PDF]

Genes Dev
Yu H, Zhang Y, Liao Z, Walters BW, Lesch BJ.   +4 more
europepmc   +1 more source

THE Paα LUMINOSITY FUNCTION OF H II REGIONS IN NEARBY GALAXIES FROMHST/NICMOS [PDF]

, 2013
Guilin Liu, Daniela Calzetti, Robert C. Kennicutt, E. Schinnerer, Yoshiaki Sofue, Shinya Komugi, Fumi Egusa, Nicholas Z. Scoville   +7 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source