Results 141 to 150 of about 2,070,514 (345)

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

Molecular Weaving of Mixed‐Addenda Polyoxometalates into MOF Nanochannels as Electron‐Buffering Reservoirs for Enhanced Nitrate‐to‐Ammonia Electrocatalysis

open access: yesAdvanced Science, EarlyView.
Synergistic interaction between P2W17V1 and FeMOF owing to its efficient proton/electron transfer affording high yield and Faradaic efficiency in electrocatalytic nitrate reduction to ammonia. ABSTRACT Electrochemical conversion of nitrate pollutants into value‐added ammonia (e‐NO3RA) offers a sustainable pathway for nitrogen valorization, yet hinges ...
Gang Li   +3 more
wiley   +1 more source

Intrinsic Negative Magnetoresistance and Broadband Photoresponse in Magnetic van der Waals Crystal TaFeTe2

open access: yesAdvanced Science, EarlyView.
2D van der Waals (vdW) materials MM′Te2 with broken symmetry attract great interest for unique magnetic structures and optical‐phonon‐induced phase transitions. We report mechanically exfoliable TaFeTe2 single crystals, exhibiting spin‐glass behavior, intrinsic unsaturated negative magnetoresistance up to 9 T, self‐powered internal photocurrent, and ...
Changcun Li   +7 more
wiley   +1 more source

Hábitos de saúde e fatores de risco em pacientes hipertensos

open access: yesRevista Latino-Americana de Enfermagem
Os objetivos deste estudo foram realizar um levantamento dos hábitos de saúde relacionados aos fatores de risco em indivíduos hipertensos hospitalizados e identificar o conhecimento dessa clientela quanto à importância do controle desses fatores para a ...
Janete Pessuto Simonetti   +2 more
doaj  

THE SEGREGATION OF TREE HABIT ON PEAR SEEDLINGS IN SIX HYBRID COMBINATIONS [PDF]

open access: green, 2007
Adriana F. Sestraş   +4 more
openalex   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

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