Results 131 to 140 of about 1,259,407 (401)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Linux Security [PDF]

open access: yes, 2017
Information age has brought a new colossal change in a person’s habitual life. The level of computer literacy has grown greatly and even a middle level specialist is able to perform the tasks intended for the programming experts.
Gubkina, V.V.   +2 more
core  

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

open access: yesFEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson   +5 more
wiley   +1 more source

The habitus of digital scholars [PDF]

open access: yesResearch in Learning Technology, 2013
This article concerns the Participatory Web and the impact it has on academic researchers’ perceptions of digital scholarship practices. The Participatory Web, as a space of active involvement, presence and socialisation of knowledge, has the potential to introduce significant changes to scholarly practice and to diversify it. This article draws on the
openaire   +6 more sources

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

Studying habit acquisition with an avoidance learning task [PDF]

open access: yes, 2015
Afiliaciones: Universidad de Málaga and Instituto de Investigación Biomédica de Málaga (IBIMA), Spain Universidad de Málaga, Spain University of Leuven, BelgiumThe study of habit acquisition and expression is considered relevant to improve our ...
Andrades, Ainhoa   +4 more
core  

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

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