Results 41 to 50 of about 117,342 (294)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Attentional Bias Associated with Habitual Self-Stigma in People with Mental Illness. [PDF]
As habitual self-stigma can have a tremendous negative impact on people with mental illness, it is of paramount importance to identify its risk factors.
Kevin K S Chan, Winnie W S Mak
doaj +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Background Self-rated health (SRH) is widely recognized as a clinically significant predictor of subsequent mortality risk. Although COVID-19 may impair SRH, this relationship has not been extensively examined.
Kentaro Matsui+27 more
doaj +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
On the incompatibility of object fronting and progressive aspect in Yucatec Maya
In this paper, we present data from an elicitation study and a corpus study that support the observation that the Yucatec Maya progressive aspect auxiliary táan is replaced by the habitual auxiliary k in sentences with contrastively focused fronted ...
Melanie Uth+2 more
doaj +1 more source
Habituation of visual adaptation [PDF]
AbstractOur sensory system adjusts its function driven by both shorter-term (e.g. adaptation) and longer-term (e.g. learning) experiences. Most past adaptation literature focuses on short-term adaptation. Only recently researchers have begun to investigate how adaptation changes over a span of days.
Dong, Xue, Gao, Yi, Lv, Lili, Bao, Min
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
De las pirámides al delito del ejercicio ilegal de la actividad financiera
Recientes defraudaciones que afectaron a una gran masa de ciudadanos motivaron al Gobierno a dictar normas al amparo de la emergencia social, con las que se modificó el Código Penal colombiano, con el propósito de sancionar severamente a los captadores ...
Hernando A. Hernández Quintero
doaj
Effect of the reinforcement rate on goal-directed and habitual choices in a multiple schedule
Voluntary behaviors can be either goal-directed, sensitive to changes in their consequences, or habitual, lacking such sensitivity. In this study, we conducted three experiments to investigate how forced-choice training influences goal-directed and ...
Ting Hu+4 more
doaj +1 more source