Results 91 to 100 of about 94,938 (303)

The Impact of Cognitive Load on the Cardiac Orienting Response to Auditory Structural Features during Natural Radio Listening Situations

open access: yesJournal of Cognition, 2018
Previous research has shown that structural features such as voice changes, jingle onsets, and production effects in a radio broadcast elicit cardiac orienting responses.
Robert F. Potter   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Resilience as a predictor of habituation

open access: yes, 2023
Habituation refers to the physiological adaptation to recurrent stressors, which can be measured by cortisol levels, and is considered a central mechanism in reducing allostatic load.
Tüscher, Oliver   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The assessment of preference with children: The effects of pre-exposure

open access: yes, 2009
This research examined the effects of relative degree of exposure (a possible establishing operation) to potential reinforcers that were non-edible (i.e., toys) on the preferences of four children who have a developmental disability. The children, ranged
Lynch, Denise Mary
core  

Time scales of auditory habituation in the amygdala and cerebral cortex [PDF]

open access: yes, 2010
Habituation is a fundamental form of learning manifested by a decrement of neuronal responses to repeated sensory stimulation. In addition, habituation is also known to occur on the behavioral level, manifested by reduced emotional reactions to ...
Seifritz, Erich   +6 more
core   +1 more source

American Black Bear–Apiary Conflicts in Michigan

open access: yesHuman-Wildlife Interactions, 2017
American black bear (Ursus americanus) damage to apiaries can result in substantial economic loss. We used records of black–bear apiary conflicts collected by the Michigan Department of Natural Resources to characterize damage in the Upper and Northern ...
Beverly K. McKinley   +2 more
doaj   +1 more source

Edmund Husserl's Phenomenology of Habituality and Habitus

open access: yesJournal of the British Society for Phenomenology, 2011
(2011). Edmund Husserl's Phenomenology of Habituality and Habitus. Journal of the British Society for Phenomenology: Vol. 42, Habit, pp. 53-77.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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