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State of the Art in Hadron Therapy
AIP Conference Proceedings, 2007Charged particle beams offer an improved dose conformation to the target volume as compared to photon radiotherapy, with better sparing of normal tissue structures close to the target. In addition, beams of ions heavier than helium exhibit a strong increase of the Linear Energy Transfer (LET) in the Bragg peak as compared to the entrance region.
Oliver Jäkel +3 more
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Radiation protection at Hadron therapy facilities
Radiation Protection Dosimetry, 2011The Italian National Centre for Oncological Hadrontherapy is currently under construction in Pavia. It is designed for the treatment of deep-seated tumours (up to a depth of 27 cm of water equivalent) with proton and C-ion beams as well as for both clinical and radiobiological research.
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Quantifying lateral tissue heterogeneities in hadron therapy
Medical Physics, 2007In radiotherapy with scanned particle beams, tissue heterogeneities lateral to the beam direction are problematic in two ways: they pose a challenge to dose calculation algorithms, and they lead to a high sensitivity to setup errors. In order to quantify and avoid these problems, a heterogeneity number as a method to quantify lateral tissue ...
D, Pflugfelder +3 more
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Fibrosis and cytokine mechanisms: Relevant in hadron therapy?
Radiotherapy and Oncology, 2004Cytokines are important for signalling between cells and tissues and constitute a humoral component of the response of cells and tissues to radiotherapy. Although several cytokines have been implicated in mediating radiation-induced reactions of normal tissues to both conventional photon and heavy ion irradiation, the mechanisms are only beginning to ...
Oliver, Haase, H Peter, Rodemann
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[Hadron therapy in carcinoma].
Medicinski arhiv, 2003According to some statistics, in the developed countries of west Europe, one in three of population will have an encounter with cancer and, only one in eight of this will have treated by use a linear accelerator. Conventional accelerator-based treatments use photon or electron or proton beams collimated to the tumour place.
Slavenka, Vobornik, Faruk, Dalagija
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La Radiologia medica, 1994
The neologism "hadrontherapy" means radiotherapy with hadrons, which are the particles constituted by quarks, such as protons, neutrons and ions. The theoretical considerations about the clinical advantages this treatment modality can yield and the results obtained at the centers where it has already been used justify the proposal to project a center ...
U, Amaldi +9 more
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The neologism "hadrontherapy" means radiotherapy with hadrons, which are the particles constituted by quarks, such as protons, neutrons and ions. The theoretical considerations about the clinical advantages this treatment modality can yield and the results obtained at the centers where it has already been used justify the proposal to project a center ...
U, Amaldi +9 more
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Hadron therapy: The clinical aspects
2018Hadron therapy, often referred to as ‘particle therapy’, includes the use of protons and carbon ions as well as other hadrons, such as pions, neutrons, helium, lithium, oxygen and silicon ions, which have been used to treat tumors. In this chapter, we only describe the use of protons and carbon ions, the charged hadrons for which the largest clinical ...
Grégoire, Vincent +3 more
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Trends in accelerator technology for hadron therapy
Physics of Particles and Nuclei Letters, 2013Hadron therapy with protons and carbon ions is one of the most effective branches in radiation oncology. It has advantages over therapy using gamma radiation and electron beams. Fifty thousand patients a year need such treatment in Russia. A review of the main modern trends in the development of accelerators for therapy and treatment techniques ...
S. A. Kostromin, E. M. Syresin
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Evolution of hadron therapy from 1935 to 2005: a personal view [PDF]
Health and TechnologyIntroduction Hadron therapy is today an established modality in cancer radiation therapy that, world-wide, is available in about hundred centres.
Ugo Amaldi
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Electron Cooling Application for Hadron Therapy
2019The project of synchrotron for hadron therapy with electron cooling is developing in Budker Institute of Nuclear Physics. The main goal of project is design of the effective and low cost hadron therapy facility. The electron cooling is applied for ion beam accumullation, cooling and preparation for the slow extraction.
Vostrikov, Vladimir +2 more
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