Results 71 to 80 of about 2,083 (199)

Production of the PET isotope ¹¹C in hadron therapy via neutron knockout [PDF]

, 2016
PURPOSE Positron emitting isotopes such as ¹¹C and ¹⁰C can be used for vital dose verification in hadron therapy. These isotopes are produced when the high energy ¹²C primary beam particles undergo nuclear reactions within the patient. METHODS We discuss
Simpson, E. C.
core   +1 more source

A comparative analysis of GEANT4, MCNP6 and FLUKA on proton‐induced gamma‐ray simulation

Medical Physics, Volume 52, Issue 6, Page 4862-4870, June 2025.
Abstract Background Precise range verification is essential in proton therapy to minimize treatment margins due to the steep dose fall‐off of proton beams. The emission of secondary radiation from nuclear reactions between incident particles and tissues stands out as a promising method for range verification. Two prominent techniques are PET and Prompt
Hugo Freitas, Esmaeil Nobakht, Florian Grüner, Joao Seco   +3 more
wiley   +1 more source

Silicon microdosimetry in hadron therapy using Geant4 [PDF]

, 2019
Hadron therapy, referring to treating cancer with protons and heavier ions, provides many advantages over conventional X-ray radiotherapy, including better dose conformity and dose sparing to healthy tissue.
David Bolst (20166573)
core  

Reconstruction from truncated projections using constrained total-variation minimization applied to PET for hadron-therapy monitoring [PDF]

, 2012
Hadron-therapy exploits light ions to treat tumors by maximizing the dose released to the target and sparing healthy tissues. With hadrons, the dose distribution rises sharply at the end of the range, providing the Bragg peak, and drops quickly to a ...
M. Rafecas, F. Diblen, Cabello, Jorge, Torres-Espallardo, Irene, Diblen, Faruk, J. E. Gillam, J. Cabello, Gillam, John, Refercas, Magdalena, I. Torres-Espallardo   +9 more
core   +1 more source

LITERATURE REVIEW ON LINACs AND FFAGs FOR HADRON THERAPY [PDF]

, 2011
The document summarizes the recent papers, presentations and other public information on Radio-Frequency (RF) Linear Accelerators (linacs) and Fixed-Field Alternating-Gradient (FFAG) accelerators for hadron therapy.
ÁNGELES FAUS-GOLFE, UGO AMALDI, SILVIA VERDÚ-ANDRÉS   +2 more
core   +1 more source

Assessing proton plans with three different beam delivery systems versus photon plans for head and neck tumors

Journal of Applied Clinical Medical Physics, Volume 26, Issue 5, May 2025.
Abstract Purpose To compare plan quality among photon volumetric modulated arc therapy (VMAT) and intensity‐modulated proton therapy (IMPT) with robustness using three different proton beam delivery systems with various spot size (σ) ranges: cyclotron‐generated proton beams (CPBs) (σ: 2.7–7.0 mm), linear accelerator proton beams (LPBs) (σ: 2.9–5.5 mm),
Tara Gray, Chieh‐Wen Liu, Saeed Ahmed, Anna Maria Kolano, Jeremy Donaghue, Shlomo Koyfman, Neil Woody, Shauna R. Campbell, Jonathan B. Farr, Ping Xia   +9 more
wiley   +1 more source

Results of a Geant4 benchmarking study for bio‐medical applications, performed with the G4‐Med system

Medical Physics, Volume 52, Issue 5, Page 2707-2761, May 2025.
Abstract Background Geant4, a Monte Carlo Simulation Toolkit extensively used in bio‐medical physics, is in continuous evolution to include newest research findings to improve its accuracy and to respond to the evolving needs of a very diverse user community.
Pedro Arce, Jay W. Archer, Lorenzo Arsini, Alexander Bagulya, David Bolst, Jeremy M. C. Brown, Barbara Caccia, Andrew Chacon, Giuseppe Antonio Pablo Cirrone, Miguel Antonio Cortés‐Giraldo, Dean Cutajar, Giacomo Cuttone, Paolo Dondero, Andrea Dotti, Bruce Faddegon, Serena Fattori, Christian Fedon, Susanna Guatelli, Akihiro Haga, Sebastien Incerti, Vladimir Ivanchenko, Dmitri Konstantinov, Ioanna Kyriakou, Albert Le, Zhuxin Li, Michel Maire, Alessandra Malaroda, Carlo Mancini‐Terracciano, Alfonso Mantero, Claire Michelet, Giuliana Milluzzo, Francesca Nicolanti, Mihaly Novak, Chihiro Omachi, Luciano Pandola, Jake Harold Pensavalle, Álvaro Perales, Yann Perrot, Giada Petringa, Silvia Pozzi, José Manuel Quesada, José Ramos‐Méndez, Francesco Romano, Anatoly B. Rosenfeld, Mitra Safavi‐Naeini, Dousatsu Sakata, Luis G. Sarmiento, Takashi Sasaki, Yoshihide Sato, Alberto Sciuto, Ioannis Sechopoulos, Edward C. Simpson, Ronny Stanzani, Alessandra Tomal, Toshiyuki Toshito, Hoang Ngoc Tran, Christopher White, Dennis H. Wright   +57 more
wiley   +1 more source

Hadron therapy in children : an update of the scientific evidence for 15 paediatric cancers [PDF]

, 2015
82 p.ill.LIST OF FIGURES 4 -- LIST OF TABLES 4 -- LIST OF ABBREVIATIONS & ACRONYMS 5 -- SCIENTIFIC REPORT 9 -- 1 INTRODUCTION 9 -- 1.1 CANCER IN CHILDREN AND ADOLESCENTS 9 -- 1.1.1 The burden of cancer in children and adolescents 9 -- 1.1.2 Prognosis 10 -
Leroy, Roos
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In vivo dosimetry for proton therapy: A Monte Carlo study of the Gadolinium spectral response throughout the course of treatment

Medical Physics, Volume 52, Issue 4, Page 2412-2424, April 2025.
Abstract Background In proton radiotherapy, the steep dose deposition profile near the end of the proton's track, the Bragg peak, ensures a more conformed deposition of dose to the tumor region when compared with conventional radiotherapy while reducing the probability of normal tissue complications.
Mariana Brás, Hugo Freitas, Patrícia Gonçalves, João Seco   +3 more
wiley   +1 more source

Charged hadron beam therapy : fast computational physics methods [PDF]

, 2012
Charged hadron beams have been investigated for use in radiation therapy of cancer since the 1940s due to their unique potential to place tightly conformal radiation doses deep inside tissue. This is achieved by exploiting the phenomenon of the so-called
Keyes, Roy William
core   +1 more source