Results 121 to 130 of about 27,999 (384)
Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′ Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar +10 morewiley +1 more sourcePossible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak +2 morewiley +1 more sourceClonal haematopoiesis and risk of chronic liver disease
Nature, 2023 W. Wong, C. Emdin, A. Bick, S. Zekavat, A. Niroula, J. Pirruccello, L. Dichtel, G. Griffin, M. Uddin, C. Gibson, Veronica Kovalcik, A. E. Lin, M. McConkey, A. Vromman, R. Sellar, Peter G Kim, M. Agrawal, J. Weinstock, M. Long, B. Yu, R. Banerjee, R. Nicholls, A. Dennis, M. Kelly, Po-Ru Loh, S. Mccarroll, E. Boerwinkle, R. Vasan, S. Jaiswal, Andrew D. Johnson, Raymond T. Chung, K. Corey, D. Levy, C. Ballantyne, Namiko Gonçalo Francois Christine Laura Alvaro Seth Peter Abe Abecasis Aguet Albert Almasy Alonso Ament Ande, Namiko Abe, G. Abecasis, F. Aguet, Christine Albert, L. Almasy, Álvaro Alonso, S. Ament, Peter Anderson, Pramod Anugu, Deborah Applebaum-Bowden, K. Ardlie, D. Arking, D. Arnett, Allison Ashley-Koch, S. Aslibekyan, T. Assimes, Paul W. Auer, D. Avramopoulos, N. Ayas, A. Balasubramanian, J. Barnard, K. Barnes, R. G. Barr, E. Barron-Casella, L. Barwick, Terri L Beaty, Gerald Beck, D. Becker, L. Becker, Rebecca Beer, A. Beitelshees, E. Benjamin, Takis Benos, Marcos Bezerra, L. Bielak, Joshua Bis, Thomas Blackwell, J. Blangero, Nathan M. Blue, D. Bowden, Russell P Bowler, Jennifer A. Brody, U. Broeckel, J. Broome, Deborah Brown, Karen L. Bunting, E. Burchard, Carlos Bustamante, Erin Buth, B. Cade, J. Cardwell, V. Carey, J. Carrier, April P. Carson, C. Carty, R. Casaburi, Juan P. Casas Romero, James M. Casella, P. Castaldi, M. Chaffin, Christy Chang, Yi-Cheng Chang, D. Chasman, S. Chavan, Bo-Juen Chen, Wei-Min Chen, Y. Chen, Michael Cho, S. Choi, Lee-Ming Chuang, M. Chung, Ren-Hua Chung, C. Clish, S. Comhair, M. Conomos, E. Cornell, A. Correa, Carolyn Crandall, J. Crapo, L. Cupples, J. Curran, J. Curtis, B. Custer, C. Damcott, D. Darbar, S. David, Colleen Davis, M. Daya, M. de Andrade, L. de las Fuentes, P. D. de Vries, Michael R. DeBaun, R. Deka, D. Demeo, Scott Devine, H. Dinh, H. Doddapaneni, Qing Duan, Shannon Dugan-Perez, R. Duggirala, J. P. Durda, S. Dutcher, Charles B. Eaton, L. Ekunwe, A. El Boueiz, P. Ellinor, L. Emery, S. Erzurum, Charles Farber, J. Farek, T. Fingerlin, M. Flickinger, M. Fornage, N. Franceschini, C. Frazar, Mao Fu, Stephanie M. Fullerton, L. Fulton, S. Gabriel, Weiniu Gan, Shanshan Gao, Yan Gao, Margery Gass, Heather Geiger, B. Gelb, M. Geraci, S. Germer, R. Gerszten, Auyon J. Ghosh, Richard Gibbs, Christopher R. Gignoux, M. Gladwin, David E. Glahn, S. Gogarten, Daoping Gong, Harald H H Goring, S. Graw, K. Gray, Daniel Grine, Colin Gross, C. Gu, Y. Guan, Xiuqing Guo, N. Gupta, J. Haessler, Michael Hall, Yi Han, P. Hanly, Daniel Harris, N. Hawley, Jiang He, Benjamin D. Heavner, S. Heckbert, Ryan Hernandez, David M. Herrington, C. Hersh, Bertha A Hidalgo, J. Hixson, B. Hobbs, J. Hokanson, Elliott Hong, Karin Hoth, C. Hsiung, Jianhong Hu, Y. Hung, H. Huston, C. Hwu, M. Irvin, Rebecca Jackson, D. Jain, C. Jaquish, J. Johnsen, Craig Johnson, R. Johnston, Kimberly Jones, H. M. Kang, R. Kaplan, S. Kardia, Shannon Kelly, E. Kenny, Michael D. Kessler, Alyna T Khan, Ziad Khan, Wonji Kim, J. Kimoff, G. Kinney, B. Konkle, C. Kooperberg, Holly Kramer, C. Lange, E. Lange, L. Lange, Cathy C. Laurie, C. Laurie, M. LeBoff, Jiwon Lee, Sandy Lee, Wen-Jane Lee, J. Lefaive, David Levine, J. Lewis, Xiaohui Li, Yun Li, Henry Lin, Honghuang Lin, Xihong Lin, Simin Liu, Yongmei Liu, Yu Liu, R. Loos, S. Lubitz, K. Lunetta, James Luo, U. Magalang, Michael P. Mahaney, B. Make, A. Manichaikul, A. Manning, J. Manson, Lisa Martin, Melissa Marton, S. Mathai, R. Mathias, Susanne May, P. McArdle, Merry-Lynn N. McDonald, Sean McFarland, S. McGarvey, Daniel McGoldrick, Caitlin P. McHugh, B. McNeil, H. Mei, J. Meigs, Vipin Menon, L. Mestroni, G. Metcalf, D. Meyers, E. Mignot, Julie Mikulla, N. Min, Mollie A Minear, R. Minster, B. Mitchell, M. Moll, Z. Momin, M. Montasser, C. Montgomery, D. Muzny, J. Mychaleckyj, Girish N. Nadkarni, Rakhi Naik, T. Naseri, S. Nekhai, Sarah C. Nelson, Bonnie Neltner, C. Nessner, Deborah A. Nickerson, Osuji Nkechinyere, Kari North, Jeffery R O'connell, T. O'Connor, H. Ochs-Balcom, Geoffrey Okwuonu, Allan Pack, David T. Paik, Nicholette D. Palmer, J. Pankow, G. Papanicolaou, Cora Parker, G. Peloso, J. Peralta, Marco V. Perez, James Perry, U. Peters, P. Peyser, Lawrence S. Phillips, Jacob Pleiness, T. Pollin, Wendy S. Post, Julia Powers Becker, Meher Preethi Boorgula, Michael H. Preuss, B. Psaty, P. Qasba, D. Qiao, Zhaohui Qin, N. Rafaels, L. Raffield, M. Rajendran, D. Rao, L. Rasmussen-Torvik, A. Ratan, S. Redline, Robert Reed, C. Reeves, E. Regan, A. Reiner, M. Reupena, Kenneth M. Rice, S. Rich, R. Robillard, N. Robine, Dan M. Roden, C. Roselli, J. Rotter, I. Ruczinski, Alexi Runnels, Pamela H. Russell, S. Ruuska, K. Ryan, E. Sabino, D. Saleheen, S. Salimi, Sejal Salvi, Steven Salzberg, Kevin Sandow, V. Sankaran, J. Santibanez, K. Schwander, D. Schwartz, F. Sciurba, C. Seidman, J. Seidman, F. Sériès, V. Sheehan, S. Sherman, Amol Shetty, Aniket Shetty, W. Sheu, M. B. Shoemaker, Brian Silver, E. Silverman, Robert Skomro, A. Smith, Jennifer A. Smith, Josh Smith, N. Smith, Tanja Smith, S. Smoller, B. Snively, M. Snyder, T. Sofer, N. Sotoodehnia, A. Stilp, G. Storm, E. Streeten, J. Su, Y. Sung, Jody Sylvia, Adam A. Szpiro, D. Taliun, Hua Tang, M. Taub, Kent D Taylor, M. Taylor, Simeon I. Taylor, M. Telen, Timothy A. Thornton, M. Threlkeld, Lesley Tinker, D. Tirschwell, S. Tishkoff, Hemant Tiwari, Catherine Tong, R. Tracy, Michael Tsai, Dhananjay Vaidya, D. J. Van Den Berg, Peter Vandehaar, S. Vrieze, Tarik Walker, R. Wallace, A. Walts, F. Wang, Heming Wang, Jiongming Wang, K. Watson, Jenn Watt, D. Weeks, Bruce Weir, Scott T. Weiss, L. Weng, J. Wessel, C. Willer, Kayleen Williams, L. Williams, Scott M. Williams, Carla Wilson, James G. Wilson, Lara Winterkorn, Q. Wong, Joseph Wu, Huichun Xu, L. Yanek, Ivana V. Yang, Ketian Yu, Yingze Zhang, Snow Xueyan Zhao, Wei Zhao, Xiaofeng Zhu, E. Ziv, M. Zody, S. Zoellner, B. Ebert, P. Natarajan +439 moresemanticscholar +1 more source
