Results 131 to 140 of about 22,415 (245)

Iron trapping in macrophages reshapes the homeostasis of the haematopoietic system. [PDF]

Br J Haematol
Crisafulli L, Correnti M, Gammella E, De Camilli E, Brindisi M, Palagano E, Milanesi C, Todisco G, Della Porta MG, Sobacchi C, Cairo G, Ficara F, Recalcati S.   +12 more
europepmc   +1 more source

Effectiveness of Autologous Hematopoietic Stem Cell Transplantation versus Alemtuzumab and Ocrelizumab in Relapsing Multiple Sclerosis: A Single Center Cohort Study

Annals of Neurology, EarlyView.
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro, Antonio Zito, Alessio Signori, Maria Pia Sormani, Eleonora Rigoni, Federica Pollidoro, Roberto Bergamaschi, Alice Mariottini, Omar Malik, Ashwini Nandoskar, Victoria Singh‐Curry, Varun Mehra, Majid Kazmi, Ian Gabriel, Eli Silber, Richard Nicholas, Antonio Scalfari   +16 more
wiley   +1 more source

The Impact of Allogeneic Hematopoietic Stem Cell Transplantation on Sickle Cell Retinopathy and Maculopathy: A Prospective, Observational Study

American Journal of Hematology, EarlyView.
Rajani P. Brandsen, Elisabeth Dovern, Bart J. Biemond, Roselie M. H. Diederen, Erfan Nur   +4 more
wiley   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Revolutionising Cardio-Oncology Care with Precision Genomics. [PDF]

Int J Mol Sci
Chong JH, Chuah CTH, Lee CG.
europepmc   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

The Effect of Anti-Activin Receptor Type IIA and Type IIB Antibody on Muscle, Bone and Blood in Healthy and Osteosarcopenic Mice. [PDF]

J Cachexia Sarcopenia Muscle
Bromer FD, Lodberg A, Eijken M, Andersen CBF, Poulsen MF, Thomsen JS, Brüel A.   +6 more
europepmc   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

The Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Anaemia predicts iron homoeostasis dysregulation and modulates the response to empagliflozin in heart failure with reduced ejection fraction: the EMPATROPISM-FE trial. [PDF]

Eur Heart J
Angermann CE, Sehner S, Gerhardt LMS, Santos-Gallego CG, Requena-Ibanez JA, Zeller T, Maack C, Sanz J, Frantz S, Ertl G, Badimon JJ.   +10 more
europepmc   +1 more source

The haematopoiesis transcription landscape [PDF]

Nature Cell Biology, 2012
openaire   +1 more source