Results 181 to 190 of about 13,881 (340)
Transcription‐independent functions of p53 in DNA repair pathway selection
BioEssays, Volume 45, Issue 1, January 2023., 2023 Transcription‐independent early recruitment and PARylation of p53 at DNA damage sites promotes the recruitment of particular repair factors (e.g. DDB1 and 53BP1) and thereby tipping the balance of repair pathway selection. Abstract
Recently discovered transcription‐independent features of p53 involve the choice of DNA damage repair pathway after ...Yu‐Hsiu Wang, Michael P. Sheetzwiley +1 more sourceBioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes
Advanced Science, EarlyView.IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...Yumeng Ma, Fanqiang Meng, Zhongda Lin, Yanjun Chen, Tianyu Lan, Zhaoxin Yang, Rui Diao, Xiaozhou Zhang, Qi Chen, Chi Zhang, Yishi Tian, Chanjuan Li, Wenli Fang, Xin Liang, Xudong Zhang +14 morewiley +1 more sourceChromosomal breaks at the origin of small tandem DNA duplications
BioEssays, Volume 45, Issue 1, January 2023., 2023 Small tandem DNA duplications form a specific mutational signature frequently found in human disease alleles and cancer genes. Here we hypothesize that these duplications mainly arise at chromosomal DNA breaks that result from two closely located single‐stranded nicks, through error‐prone repair by the non‐homologous end‐joining pathway. Abstract
Small Joost Schimmel, Marloes D. van Wezel, Robin van Schendel, Marcel Tijsterman +3 morewiley +1 more sourceInherited causes of clonal haematopoiesis in 97,691 whole genomes
Nature, 2020 A. Bick, J. Weinstock, Satish K. Nandakumar, C. Fulco, Erik L. Bao, S. Zekavat, M. Szeto, Xiaotian Liao, Matthew J. Leventhal, J. Nasser, K. Chang, Cecelia Laurie, B. Burugula, C. Gibson, A. Niroula, A. E. Lin, M. Taub, F. Aguet, K. Ardlie, B. Mitchell, K. Barnes, A. Moscati, M. Fornage, S. Redline, B. Psaty, E. Silverman, S. Weiss, Nicholette D. Palmer, R. Vasan, E. Burchard, S. Kardia, Jiang He, R. Kaplan, N. Smith, D. Arnett, D. A. Schwartz, A. Correa, M. de Andrade, Xiuqing Guo, B. Konkle, B. Custer, J. Peralta, H. Gui, D. Meyers, S. McGarvey, I. Chen, M. B. Shoemaker, Patricia A. Peyser, J. Broome, S. Gogarten, F. Wang, Q. Wong, M. Montasser, M. Daya, E. Kenny, K. North, L. Launer, B. Cade, J. Bis, M. Cho, J. Lasky-Su, Don Bowden, L. Cupples, Angel C. Y. Mak, L. Becker, Jennifer A. Smith, T. Kelly, Stella Aslibekyan, S. Heckbert, Hemant K. Tiwari, Ivana V. Yang, J. Heit, S. Lubitz, J. Johnsen, J. Curran, S. Wenzel, D. Weeks, D. Rao, D. Darbar, Jee-Young Moon, R. Tracy, Erin Buth, N. Rafaels, R. Loos, P. Durda, Yongmei Liu, L. Hou, Jiwon Lee, P. Kachroo, B. Freedman, D. Levy, Lawrence F. Bielak, J. Hixson, J. Floyd, E. Whitsel, P. Ellinor, M. Irvin, T. Fingerlin, L. Raffield, Sebastian M. Armasu, Marsha M. Wheeler, E. Sabino, J. Blangero, L. Williams, B. Levy, W. Sheu, D. Roden, E. Boerwinkle, J. Manson, R. Mathias, Pinkal M. Desai, K. Taylor, Andrew D. Johnson, Namiko Christine Laura Alvaro Seth Peter Pramod Deborah D Abe Albert Almasy Alonso Ament Anderson Anugu Appl, Namiko Abe, Christine Albert, L. Almasy, Álvaro Alonso, S. Ament, Peter Anderson, Pramod Anugu, Deborah Applebaum-Bowden, D. Arking, Allison Ashley-Koch, Stella Aslibekyan, T. Assimes, D. Avramopoulos, J. Barnard, R. G. Barr, E. Barron-Casella, L. Barwick, Terri L Beaty, Gerald Beck, D. Becker, Rebecca Beer, A. Beitelshees, E. Benjamin, P. Benos, Marcos Bezerra, Larry Bielak, Russell P Bowler, Jennifer A. Brody, U. Broeckel, Karen L. Bunting, Carlos Bustamante, J. Cardwell, V. Carey, C. Carty, R. Casaburi, James M. Casella, P. Castaldi, M. Chaffin, Christy Chang, Yi-Cheng Chang, D. Chasman, S. Chavan, Bo-Juen Chen, Wei-Min Chen, S. Choi, Lee-Ming Chuang, M. Chung, R. Chung, C. Clish, S. Comhair, E. Cornell, Carolyn Crandall, J. Crapo, J. Curtis, C. Damcott, Sayantan Das, S. David, Colleen Davis, Michael R. DeBaun, R. Deka, D. Demeo, Scott Devine, Qing Duan, R. Duggirala, S. Dutcher, Charles B. Eaton, L. Ekunwe, A. Boueiz, L. Emery, S. Erzurum, Charles Farber, M. Flickinger, N. Franceschini, C. Frazar, Mao Fu, Stephanie M. Fullerton, L. Fulton, S. Gabriel, Weiniu Gan, Shanshan Gao, Yan Gao, Margery Gass, B. Gelb, Xiaoqi (Priscilla) Geng, M. Geraci, S. Germer, R. Gerszten, Auyon J. Ghosh, Richard Gibbs, Christopher R. Gignoux, M. Gladwin, David E. Glahn, Daoping Gong, Harald H H Goring, S. Graw, Daniel Grine, C. Gu, Y. Guan, N. Gupta, J. Haessler, Michael Hall, Daniel Harris, N. Hawley, Benjamin D. Heavner, Ryan Hernandez, David M. Herrington, C. Hersh, Bertha A Hidalgo, B. Hobbs, J. Hokanson, Elliott Hong, K. Hoth, Chao (Agnes) Hsiung, Y. Hung, H. Huston, C. Hwu, Rebecca Jackson, D. Jain, C. Jaquish, Min A. Jhun, Craig Johnson, R. Johnston, Kimberly Jones, H. M. Kang, Shannon Kelly, Michael D. Kessler, Alyna T Khan, Wonji Kim, G. Kinney, Holly Kramer, C. Lange, M. LeBoff, S. Lee, Wen-Jane Lee, J. Lefaive, David Levine, J. Lewis, Xiaohui Li, Yun Li, Henry Lin, Honghuang Lin, Keng-Han Lin, Xihong Lin, Simin Liu, Yu Liu, K. Lunetta, James Luo, Michael P. Mahaney, B. Make, A. Manichaikul, L. Margolin, Lisa Martin, S. Mathai, Susanne May, P. McArdle, Merry-Lynn N. McDonald, Sean McFarland, Daniel McGoldrick, Caitlin P. McHugh, H. Mei, L. Mestroni, Julie Mikulla, N. Min, Mollie A Minear, R. Minster, M. Moll, C. Montgomery, S. Musani, Stanford E. Mwasongwe, J. Mychaleckyj, Girish N. Nadkarni, Rakhi Naik, T. Naseri, S. Nekhai, Sarah C. Nelson, Bonnie Neltner, D. Nickerson, Jeffery R O'connell, T. O'Connor, H. Ochs-Balcom, D. Paik, J. Pankow, G. Papanicolaou, A. Parsa, Marco V. Perez, James Perry, U. Peters, Patricia Peyser, Lawrence S. Phillips, T. Pollin, Wendy S. Post, Julia Powers Becker, M. Boorgula, Michael H. Preuss, P. Qasba, D. Qiao, Zhaohui Qin, L. Rasmussen-Torvik, A. Ratan, Robert Reed, E. Regan, Muagututi’a Sefuiva Reupena, Kenneth M. Rice, C. Roselli, I. Ruczinski, Pamela H. Russell, S. Ruuska, K. Ryan, D. Saleheen, S. Salimi, Steven Salzberg, Kevin Sandow, Christopher Scheller, Ellen M. Schmidt, K. Schwander, F. Sciurba, C. Seidman, J. Seidman, V. Sheehan, Stephanie L. Sherman, Amol Shetty, Aniket Shetty, Brian Silver, Josh Smith, Tanja Smith, S. Smoller, B. Snively, M. Snyder, T. Sofer, N. Sotoodehnia, A. Stilp, G. Storm, E. Streeten, J. Su, Y. Sung, Jody Sylvia, Adam A. Szpiro, C. Sztalryd, D. Taliun, Hua Tang, M. Taylor, Simeon I. Taylor, M. Telen, T. Thornton, M. Threlkeld, Lesley Tinker, D. Tirschwell, S. Tishkoff, Hemant K. Tiwari, Catherine Tong, Michael Tsai, Dhananjay Vaidya, D. V. Berg, Peter Vandehaar, S. Vrieze, Tarik Walker, R. Wallace, A. Walts, Heming Wang, K. Watson, Bruce Weir, L. Weng, J. Wessel, C. Willer, Kayleen Williams, Carla Wilson, Joseph Wu, Huichun Xu, L. Yanek, Rongze Yang, N. Zaghloul, Yingze Zhang, Snow Xueyan Zhao, Wei Zhao, Degui Zhi, Xiang Zhou, Xiaofeng Zhu, M. Zody, S. Zoellner, P. Auer, C. Kooperberg, Cathy C. Laurie, T. Blackwell, A. Smith, Hongyu Zhao, E. Lange, L. Lange, S. Rich, J. Rotter, James G. Wilson, P. Scheet, J. Kitzman, E. Lander, J. Engreitz, B. Ebert, A. Reiner, S. Jaiswal, G. Abecasis, V. Sankaran, S. Kathiresan, P. Natarajan +414 moresemanticscholar +1 more sourceGfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non‐overlapping functions in inner ear development
, 2006 Katharina Fiolka, Ronna Hertzano, Lothar Vaßen, Hui Zeng, Orit Hermesh, Karen B. Avraham, Ulrich Dührsen, Tarik Möröy +7 moreopenalex +1 more source
