Results 191 to 200 of about 24,687 (303)

Extramedullary haematopoiesis

, 2020
openaire   +2 more sources

Harmonising ctDNA Measurement in Haematological Malignancies: Traceability, Commutability and Reporting. [PDF]

Diagnostics (Basel)
Shibeeb S.
europepmc   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Prognostic and therapeutic implications of TP53 expression in chronic myelomonocytic leukemia

Blood Cancer Journal
Yu-Hung Wang, Chien-Chin Lin, Kristian Gurashi, Chi-Yuan Yao, Andres Jerez, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Kiran Batta, Daniel H. Wiseman   +9 more
doaj   +1 more source

Clonal haematopoiesis of indeterminate potential and risk of incident psychiatric disorders. [PDF]

BMC Med
Yu Y, Wan C, Li J, Sun Y, Yu B, Tan X, Wang B, Lu Y, Wang N.   +8 more
europepmc   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Intrinsic and niche-dependent metabolic regulation of haematopoietic stem cells and implications for leukaemogenesis. [PDF]

Nat Cell Biol
Erdem A, Morganti C, Totani H, van Gastel N, Ito K.   +4 more
europepmc   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Editorial: Plasticity of the haematopoietic niche: from embryonic development to aging and disease. [PDF]

Front Mol Biosci
Sugimura R, Fidanza A, Azzoni E, Canu G.
europepmc   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source