Results 261 to 270 of about 24,687 (303)
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Intrathoracic extramedullary haematopoiesis
Postgraduate Medical Journal, 2019A woman from the Middle East, in her fifth decade, known to have beta thalassemia while undergoing routine medical assessment was incidentally detected to have a mass lesion in the right lower zone on chest radiograph (figure 1). On clinical assessment she was found to have hepatosplenomegaly. Respiratory system examination was unremarkable.
Padmanabhan Arjun, Mathew Thomas
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Updates on Old and Weary Haematopoiesis [PDF]
International Journal of Molecular Sciences, 2018 Blood formation, or haematopoiesis, originates from haematopoietic stem cells (HSCs), whose functions and maintenance are regulated in both cell- and cell non-autonomous ways. The surroundings of HSCs in the bone marrow create a specific niche or microenvironment where HSCs nest that allows them to retain their unique characteristics and respond ...
Lorena Arranz
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Cellular interactions in haematopoiesis
Nature, 1979In vitro culture of haematopoietic cells has provided some surprising insights into critical interactions of blood-forming cells. Subpopulations of lymphoid cells have been shown to produce colony-stimulating activity, to interact with macrophages, and to have important effects on the very early stages of erythropoiesis.
M J, Cline, D W, Golde
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Developmental & Comparative Immunology, 2016
Marsupials are a group of mammals that give birth to immature young lacking mature immune tissues at birth, and are unable to mount their own specific immune defence. Their immune tissues develop in a non-sterile ex-utero environment unlike that of eutherian mammals such as ourselves.
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Marsupials are a group of mammals that give birth to immature young lacking mature immune tissues at birth, and are unable to mount their own specific immune defence. Their immune tissues develop in a non-sterile ex-utero environment unlike that of eutherian mammals such as ourselves.
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Cohesin in haematopoiesis and leukaemia
Current Opinion in Hematology, 2018Purpose of review Disturbance of the delicate balance between self-renewal and differentiation in haematopoietic stem cells (HSCs) can lead to both leukaemia and bone marrow failure. The regulation of this balance in HSC biology has been intensely investigated in several model systems, and lately the importance of epigenetic ...
Roman, Galeev, Jonas, Larsson
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Adrenergic regulation of haematopoiesis
Pharmacological Research, 1995In spite of many reports demonstrating the presence of sympathetic fibres innervating the bone marrow, the evidence for a direct adrenergic influence on haematopoiesis is a recent finding. This review concentrates on recent work on the role of adrenergic agents in haematopoiesis.
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The role of cytokines in haematopoiesis
European Journal of Haematology, 1996Abstract: Cytokines, by definition, exert an effect on haematopoiesis. Diseases characterized by haematopoietic insufficiency, such as aplastic anaemia, should therefore be investigated for abnormal expression of these regulatory proteins. In studies on hairy cell leukaemia, a severe deficiency was found in the production of interleukin‐3 (IL‐3 ...
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Ikaros: a key regulator of haematopoiesis
The International Journal of Biochemistry & Cell Biology, 2002Ikaros is an essential transcription factor for normal lymphocyte development. Because of its interaction with a number of closely related factors, Ikaros is required for correct regulation of differentiation and cell proliferation in T- and B-cell lineages.
Belinda J, Westman +2 more
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