Multisite clinical cross-validation and variant interpretation of a next generation sequencing panel for lymphoid cancer prognostication. [PDF]
Sabatini PJB+11 more
europepmc +1 more source
Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin+2 more
wiley +1 more source
Single-cell multi-omics analysis identifies context-specific gene regulatory gates and mechanisms. [PDF]
Malekpour SA, Haghverdi L, Sadeghi M.
europepmc +1 more source
Haematopoiesis in drug-induced agranulocytosis
openaire +3 more sources
Building a human lung from pluripotent stem cells to model respiratory viral infections. [PDF]
Turner DL+4 more
europepmc +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan+13 more
wiley +1 more source
Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. [PDF]
Laing A+11 more
europepmc +1 more source
A case of anti-CD320 antibody-positive cutaneous arteritis accompanied by multiple cranial nerve symptoms. [PDF]
Hasegawa A+6 more
europepmc +1 more source
Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia. [PDF]
Lints R+6 more
europepmc +1 more source
Can molecular patterns help to classify overlapping entities in myeloid neoplasms? [PDF]
Hoermann G, Khoury JD.
europepmc +1 more source