Results 71 to 80 of about 22,731 (338)
Molecular mechanisms in haematological malignancies [PDF]
, 2009 Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto +2 more
core
Regulation of NF-κB by PML and PML-RARα [PDF]
, 2017 Promyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation.
Ahmed, Abrar +8 more
core +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Unraveling the history of limb bones
eLife, 2021 Ancient fossils give clues as to when features of modern tetrapod bones emerged.
Holly N Woodward
doaj +1 more source
Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]
, 2018 La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core
Human Haematopoietic Stem Cell Heterogeneity in Postnatal Haematopoiesis and Ontogeny [PDF]
, 2021 Haematopoietic stem cell (HSC) transplants are upheld as one of the most successful therapies in regenerative medicine. While improved purification and functionality assays have advanced understanding of steady-state haematopoiesis and the human bona ...
Popova, Semiramis
core
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
eLife, 2021 Plasmodium vivax is the major cause of human malaria in the Americas. How P. vivax infection can lead to poor clinical outcomes, despite low peripheral parasitaemia, remains a matter of intense debate. Estimation of total P.
João L Silva-Filho +11 more
doaj +1 more source
Ribosomal proteins in zebrafish haematopoiesis and human disease [PDF]
, 2011 PhDSeveral congenital disorders of human haematopoiesis including Diamond- Blackfan anaemia result from heterozygous loss of genes involved in ribosome biogenesis.
Payne, Elspeth
core
The changing face of haematopoiesis: A spectrum of options is available to stem cells [PDF]
, 2018 For more than 30 years, the scheme whereby bone marrow hematopoietic stem cells give rise to the many different types of blood and immune cells has been represented as a lineage tree diagram.
Brown, Geoffrey +2 more
core +1 more source