Results 91 to 100 of about 405,460 (280)

Tumour-infiltrating Lymphocyte Score and its Association with Histopathological Parameters in Gastrointestinal Tumours: A Cross-sectional Study from a Tertiary Care Centre in Chengalpattu, Tamil Nadu, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Gastrointestinal malignancies are biologically heterogeneous and show variable immune responses across anatomical sites. Tumour-Infiltrating Lymphocytes (TIL) reflects host immune response within the tumour microenvironment and can be ...
Anushankari Pandian, Sangeetha Nagalingam   +1 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Haematoxylin and Eosin stained sections of liver (panel a) and heart (panel b), obtained from the five mice groups 6 months after the start of the hypercaloric diets and imaged in a Nikon Eclipse 80i upright microscope at 20×. [PDF]

, 2014
Haematoxylin and Eosin stained sections of liver (panel a) and heart (panel b), obtained from the five mice groups 6 months after the start of the hypercaloric diets and imaged in a Nikon Eclipse 80i upright microscope at 20×.
Mayte Montero (658098), Rosalba I. Fonteriz (658100), Javier Alvarez (658102), Sergio de la Fuente (658099), Alfredo Moreno (658101)   +4 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Number of positive minor salivary glands (MSG) samples according to the presence of at least one focus scored as possible germinal center (GC)-like structure by the operators (Op) on haematoxylin and eosin (H&E) or by different histological techniques. [PDF]

, 2019
Number of positive minor salivary glands (MSG) samples according to the presence of at least one focus scored as possible germinal center (GC)-like structure by the operators (Op) on haematoxylin and eosin (H&E) or by different histological techniques.
Alessia Alunno (290618), Roberto Giacomelli (55207), Roberto Gerli (290624), Elena Bartoloni (290620), Gianluca Cipolloni (6265454), Mirko Manetti (755227), Paola Cipriani (55208), Gino Coletti (6265445), Barbara Bigerna (6265448), Vasiliki Liakouli (3684820), Paola Di Benedetto (2478967), Piero Ruscitti (3684799), Francesco Carubbi (3684811), Onelia Bistoni (6265451)   +13 more
core   +1 more source

Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole

npj Digital Medicine
Distinguishing histological subtypes of early pregnancy loss is crucial for clinical practice. Current gold standards combining pathological and molecular profiling are costly, limiting implementation.
Yating Zhao, Xinhui He, Xin Ye, Zhe Wang, Bo Huang, Jiaqi Ning, Limeng Cai, Peilin Han, Huifang Zhang, Hao Chen, Xiangang Yin, Jie Dong, Ping Duan, Huafeng Shou, Qingmei Han, Kai Yan, Jing Zhang, Min Hu, Ruiqi Sun, Qihong Wan, Xiupu Liu, Qiwei Zheng, Wanting Huang, Haixia Luo, Jue Xie, Xiaofei Zhang, Xiang Tian, Jianhua Qian   +27 more
doaj   +1 more source

Comparative Study of Crystal Violet Stain and Haematoxylin and Eosin Stain in the Assessment of Mitotic Figures in Dysplastic and Malignant Lesions of Oral Cavity [PDF]

Journal of Krishna Institute of Medical Sciences University, 2021
Background: Mitotic figures are valuable tool in assessing cellular proliferation and act as a prognostic indicator in dysplastic and malignant lesions of oral cavity.
Nayantrishna Nath , Surekha Ulhas Arakeri   +1 more
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Bang and the Artefacts are Gone! Rapid Artefact Removal and Tissue Segmentation in Haematoxylin and Eosin Stained Biopsies

, 2023
Abstract We present H&E Otsu thresholding, a scheme for rapidly detecting tissue in whole-slide images (WSIs) that eliminates a wide range of undesirable artefacts such as pen marks and scanning artefacts. Our method involves obtaining a bimodal representation of a low-magnification RGB overview image which enables simple Otsu thresholding ...
B. A. Schreiber, J. Denholm, F. Jaeckle, M. J. Arends, Kim M. Branson, Carola-Bibiane Schönlieb, E. J. Soilleux   +6 more
openaire   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source