Results 81 to 90 of about 405,460 (280)

Quantitative assessment of H&E staining for pathology: development and clinical evaluation of a novel system

Diagnostic Pathology
Background Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sample.
Catriona Dunn, David Brettle, Martin Cockroft, Elizabeth Keating, Craig Revie, Darren Treanor   +5 more
doaj   +1 more source

Staining Potentials of Indigenous Hibiscus Sabdariffa Calyx and Lawsonia inermis Leaves on Liver and Kidney Tissues

Sokoto Journal of Medical Laboratory Science, 2020
In view of the hazards associated with the use of synthetic stains and the escalating cost of foreign dyes, it has become essential to seek for natural, economic, easy to use, biodegradable, safe (to both human and environmental health) and more eco ...
Okolie, N. ; Ngokere, A. and Enweani, I.
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Retrolental vascular membrane in a case of ciliary body medulloepithelioma: Clinicopathologic correlation

The Pan-American Journal of Ophthalmology, 2019
A unilateral nonteratoid malignant ciliary body medulloepithelioma presented in a 13-year-old girl as a leukocoria with an extense vascularized retrolental membrane in her right eye.
Luca Bongiovanni De Miranda Gonçalves, Joao Carlos De Miranda Gonçalves, Maria Cristina Martins, Miguel N Burnier   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

HAEMATOXYLIN AND EOSIN STAINING IN THE DIAGNOSIS OF HODGKIN’S DISEASE IN UGANDA [PDF]

, 2011
Background: Whereas immunohistochemical methods have been widely used for thediagnosis and classification of Hodgkin’s Disease in the developed countries, there arevery few reports of their use in the developing countries where haematoxylin and eosinis ...
ODIDA, M., WABINGA, H.R., TUMWINE, L.K.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Stain Removal Through Color Normalization of Haematoxylin and Eosin Images: A Review

Journal of Physics: Conference Series, 2019
Abstract Histopathology images are used for the diagnosis and examination of cancer cells. Preparing and scanning histopathology slides consist of numerous steps of which staining are an important process. But these staining procedures cause multitude problems as there may be variations in the slides due to multiple reasons.
B. Lakshmanan, S. Anand, T. Jenitha
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source