A pilot study on the prevalence and patterns of haemoglobinopathies in Datia District, Madhya Pradesh, India [PDF]
Scientific ReportsHaemoglobinopathies are the most common inherited disorder of Red Blood Cells across the globe and one of the major public health problems in many regions of India. Variation in ethnic and regional prevalence is observed in many parts of India.
S. Rajasubramaniam +6 more
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Haemoglobinopathies: A Retrospective Study from a Tertiary Care Centre, Southern India [PDF]
National Journal of Laboratory Medicine, 2022 Introduction: Thalassaemia and other structural haemoglobinopathies are the major genetic disorders that cause significant morbidity in children. Haemoglobinopathies need to be diagnosed at the earliest in order to offer suitable treatment, carrier ...
Hemalata Lokanatha, Pradeep Rudramurthy
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Machine Learning‐Based Detection of HbS and HbC Carriers in the UK General Population [PDF]
eJHaemBackground Haemoglobin S (HbS) and C (HbC) are the most important sickling variants on the African continent, imposing major health burdens. Early detection of carrier status is crucial but often hindered by resource limitations.
Frederik Christensen +7 more
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A Comparative Analysis of Haemoglobinopathy Diagnostic Techniques—The Ghanaian Picture and the Way Forward: A Narrative Review [PDF]
Health Science ReportsIntroduction and Aim Although there are efficient methods for diagnosing haemoglobinopathies all over the world, their widespread application in Ghana is constrained by cost, infrastructure issues, and restricted access.
Stephen Twumasi +4 more
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Prevalence of Haemoglobinopathies in Children Presenting with Anemia at DHQ Hospital Zhob, Balochistan [PDF]
JLUMHS, 2021 OBJECTIVE: To find the prevalence of haemoglobinopathies in children presenting with anemia at District Headquarter Hospital Zhob. METHODOLOGY: The cross-sectional study was carried out at District Headquarter Hospital (DHQ) Zhob from March to August ...
Sumera Akram +4 more
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Spectrum of Haemoglobinopathies Detected on Antenatal Screening and Diagnostic Work-up in an Urban Healthcare Set-up: A Retrospective Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Haemoglobinopathies are inherited disorders of Haemoglobin (Hb) and consist of Thalassemias and many other structurally variant haemoglobins. Out of these, beta-thalassemia major and clinically significant sickle cell disorders are of great
Susan Cherian +4 more
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Journal of Cardiovascular Development and Disease, 2021 Beta-thalassemia major (β-TM) is a hereditary genetic disease worsened by many comorbidities due to transfusion-related iron despite chelation therapy. Since there has recently been an increase in life expectancy of patients to up to 50 years old, which ...
Umberto Barbero +5 more
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Burden of Congenital Haemolytic Anaemias among the Rural Paediatric Population of Central India [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Childhood anaemia may be caused due to many factors, including malnutrition, chronic infections, deficiency of iron and vitamins, parasitic infections.
Manal Ashraf Ali +2 more
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Frequency and Patterns of Bacteraemia in Children with Sickle Cell Disease: A Prospective Cohort Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Sickle Cell Disease (SCD) is one of the most common inherited haemoglobinopathies and is associated with high morbidity and mortality, particularly in early childhood among the affected population. Infection is a significant contributor
Syed Athhar Saqqaf +5 more
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African Journal of Laboratory Medicine, 2023 Background: Haemoglobinopathies, including sickle cell disease and β-thalassaemia, are monogenic disorders with a relatively higher prevalence among malaria-endemic areas in Africa.
Seth Twum +3 more
doaj +1 more source