Results 181 to 190 of about 21,171,014 (388)

Carotid Intima‐Media Thickness as a Marker of Subclinical Atherosclerosis in Adolescents With Severe Haemophilia

Haemophilia, EarlyView.
ABSTRACT Background The clinical focus of haemophilia has expanded beyond bleeding outcomes to encompass long‐term comorbidities such as cardiovascular disease (CVD). However, it remains unclear when vascular changes begin in this population. Carotid intima‐media thickness (cIMT), a validated, non‐invasive marker of subclinical atherosclerosis, may ...
Alyson Trillo, Juanita Hunter, Audrey Ofir, Jamie Shoag, Joanna A. Davis, Fernando F. Corrales‐Medina   +5 more
wiley   +1 more source

Prophylaxis in Hemophilia A Patients with Inhibitors [PDF]

, 2013
The development of antibodies to factor VIII is one of the most serious complications of haemophilia treatment. Approximately 30% of patients with severe haemophilia develop neutralizing inhibitors to replacement FVIII.
Antunes, M, Diniz, MJ, Santos, A
core  

Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates

, 2022
Jonathan R Day, Clifford M. Takemoto, Anjali Sharathkumar, Sarah Makhani, Ashwin Gupta, Stephanie Bitner, Cassandra D. Josephson, Evan M. Bloch, Aaron A.R. Tobian, Lakshmanan Krishnamurti, Ruchika Goel   +10 more
openalex   +1 more source

Simplifying surgery in haemophilia B: Low factor IX consumption and infrequent infusions in surgical procedures with rIX-FP [PDF]

, 2020
Julie Curtin, Elena Santagostino, Faraizah Abdul Karim, Yanyan Li, Wilfried Seifert, Claude Négrier   +5 more
openalex   +1 more source

Haemophilia, state of the art and new therapeutic opportunities, a regulatory perspective [PDF]

, 2021
Francesca Tomeo, Segundo Mariz, Angelo Loris Brunetta, Violeta Stoyanova‐Beninska, Karri Penttilä, Armando Magrelli   +5 more
openalex   +1 more source

Outcomes of Emicizumab Treatment for Haemophilia A Paediatric Patients: A Systematic Review With Meta‐Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia A in paediatric patients presents a lifelong risk of spontaneous and trauma‐induced haemorrhage, leading to progressive joint damage, disability and impaired quality of life. Emicizumab, a bispecific monoclonal antibody administered subcutaneously, offers sustained haemostatic protection and has shown promising ...
Konstantina Bolou, George Triantafyllou, Athina Dettoraki, Aikaterini Michalopoulou, Miltiades Kyprianou, Olympia Papakonstantinou, Helen Pergantou   +6 more
wiley   +1 more source

Effects of primary and secondary prophylaxis on the clinical expression of joint damage in children with severe haemophilia A [PDF]

, 2007
Karin Kurnik, Frauke Friedrichs, Susan Halimeh, Anne Krümpel, Christoph Bidlingmaier, R. Schobeß, Ulrike Nowak‐Göttl   +6 more
openalex   +1 more source

Exploring the Effects of Factor Xa Inhibitors on Thrombin Generation in People with Haemophilia

, 2023
Caroline Dix, James D. McFadyen, Huyen Tran   +2 more
openalex   +1 more source

Acceptability and Determinants for Implementation of the EnzySystem, a Novel Near‐Patient Testing Platform for Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Coagulation testing in haemophilia A is limited by the scarcity of testing facilities capable of performing relevant assays. This issue incentivized the development of the EnzySystem for haemophilia A, a near‐patient testing platform aimed to measure Factor VIII activity and thrombin generation simultaneously within 1 h from 100 ...
Aernoud P. Bavinck, Kyle Davis, Lisa van Engelshoven, Monique G. van Lier, Tanja Hamacher, Nicole M. A. Blijlevens, Amy Shapiro, Saskia E. M. Schols, Waander L. van Heerde   +8 more
wiley   +1 more source

Racial and ethnic differences in reported haemophilia death rates in the United States [PDF]

, 2023
Stacey A. Fedewa, Amanda B. Payne, Duc Quang Tran, Lorraine Cafuir, Ana G. Antun, Christine L. Kempton   +5 more
openalex   +1 more source