Lithuanian haemophilia A and B registry comprising phenotypic and genotypic data [PDF]
Vytautas Ivaškevičius+9 more
openalex +1 more source
ABSTRACT Introduction Haemophilia is a bleeding disorder caused by a deficiency in coagulation factors VIII or IX. Great advances in haemophilia treatment have been achieved in recent decades, with a range of products for prophylaxis now available, the ability to individualise therapy, and resultant improvements in life expectancy and quality of life ...
Allison P. Wheeler+6 more
wiley +1 more source
Haemophilia B mutations in Sweden: a population‐based study of mutational heterogeneity [PDF]
Rolf Ljung+3 more
openalex +1 more source
Factors Influencing Symptoms of Depression, Anxiety and Stress in Patients With Haemophilia
ABSTRACT Introduction Patients with haemophilia (PwH) often suffer from psychological symptoms such as depression or anxiety. To date, uncertainty exists about the determinants predicting worse psychological outcomes. Therefore, this study aimed to investigate the extent of depressive, anxiety and stress‐related symptoms in PwH compared to the healthy ...
Alexander Schmidt+7 more
wiley +1 more source
Mutation analysis and characterisation of F9 gene in haemophilia- B population of India. [PDF]
Kulkarni S+8 more
europepmc +1 more source
A protocol for the dental management of von Willebrand's disease, haemophilia A and haemophilia B [PDF]
Malcolm J. Stubbs, J. V. Lloyd
openalex +1 more source
ABSTRACT Introduction Currently, physical health assessments in persons with haemophilia focus on bleed‐related events and after‐effects. The aim of the systematic review was to review and apply standardised criteria to evaluate reliability, responsiveness and construct validity of performance‐based instruments evaluating physical capability in persons
Catherine Holdsworth+9 more
wiley +1 more source
Quality of life in a large multinational haemophilia B cohort (The B-Natural study) - Unmet needs remain. [PDF]
Berntorp E+27 more
europepmc +1 more source
Safety and Use of Eptacog Beta 225 µg/kg in Patients With Haemophilia A or B With Inhibitors
Introduction Eptacog beta is an activated recombinant human factor VII bypassing agent approved for treating bleeding episodes (BEs) in patients aged ≥12 years with haemophilia A or B with inhibitors. Two initial dose regimens (IDRs) of either 75 or 225 µg/kg, followed by 75 µg/kg, are approved.
Manuel Carcao+7 more
wiley +1 more source
Preclinical development of plant-based oral immune modulatory therapy for haemophilia B. [PDF]
Srinivasan A+6 more
europepmc +1 more source