Results 121 to 130 of about 12,413,959 (307)

Integration of Efanesoctocog Alfa in Clinical Practice for Children, Adolescents, and Young Adults With Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Efanesoctocog alfa is a novel, “ultra‐extended half‐life” FVIII concentrate for bleed treatment and prevention in haemophilia A. Clinical trials excluded individuals with active or prior FVIII inhibitors, those on emicizumab, and previously untreated patients (PUPs).
Debbie Jiang, Natalie Johnston, Daniel Echelman, Stacy E. Croteau   +3 more
wiley   +1 more source

Evaluation of the Burden of Bone Fractures in People Living With Haemophilia: A Registry‐Based Matched Cohort Study

Haemophilia, EarlyView.
ABSTRACT Background Bone diseases, such as low bone mineral density and osteoporosis is an emerging concern in people with haemophilia (PWH). As a consequence, PWH might experience fractures more frequently than the general population. Our primary aim was to compare the incidence of bone fractures in PWH and controls without bleeding disorders.
Federico Germini, Arun Keepanasseril, Quazi Ibrahim, Emma Iserman, Alfonso Iorio, Chatree Chai‐Adisaksopha, Davide Matino   +6 more
wiley   +1 more source

Use of extended half-life factor IX products in the surgical setting: case series from a UK haemophilia centre

The Journal of Haemophilia Practice
For people with haemophilia, surgical procedures, whether haemophilia-related or for other conditions, are associated with a risk of bleeding. Factor activity levels must be maintained for any invasive intervention.
Ndebele Molly, Charnick Emma, Asir Nawal, Aradom Elsa   +3 more
doaj   +1 more source

International Practices in Managing Preconception, Pregnancy and Childbirth in Women With Glanzmann Thrombasthenia: A Survey From the European Association of Haemophilia and Allied Disorders (EAHAD)

Haemophilia, EarlyView.
ABSTRACT Background Glanzmann thrombasthenia (GT) is an inherited platelet disorder resulting in severely reduced platelet aggregation and increased bleeding tendency. Pregnancy and childbirth in women with GT present significant challenges for both mother and child.
Karlijn H. G. Rutten, Roger E. G. Schutgens, Roseline d'Oiron, Mathieu Fiore, Giancarlo Castaman, Keith Gomez, Mary Mathias, Michelle Lavin, Petra Elfvinge, Rezan Abdul Kadir, Karin P. M. van Galen, the Glanzmann Thrombasthenia and Women and Girls with Bleeding Disorders Working Groups of the EAHAD   +11 more
wiley   +1 more source

Carotid Intima‐Media Thickness as a Marker of Subclinical Atherosclerosis in Adolescents With Severe Haemophilia

Haemophilia, EarlyView.
ABSTRACT Background The clinical focus of haemophilia has expanded beyond bleeding outcomes to encompass long‐term comorbidities such as cardiovascular disease (CVD). However, it remains unclear when vascular changes begin in this population. Carotid intima‐media thickness (cIMT), a validated, non‐invasive marker of subclinical atherosclerosis, may ...
Alyson Trillo, Juanita Hunter, Audrey Ofir, Jamie Shoag, Joanna A. Davis, Fernando F. Corrales‐Medina   +5 more
wiley   +1 more source

Outcomes of Emicizumab Treatment for Haemophilia A Paediatric Patients: A Systematic Review With Meta‐Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia A in paediatric patients presents a lifelong risk of spontaneous and trauma‐induced haemorrhage, leading to progressive joint damage, disability and impaired quality of life. Emicizumab, a bispecific monoclonal antibody administered subcutaneously, offers sustained haemostatic protection and has shown promising ...
Konstantina Bolou, George Triantafyllou, Athina Dettoraki, Aikaterini Michalopoulou, Miltiades Kyprianou, Olympia Papakonstantinou, Helen Pergantou   +6 more
wiley   +1 more source

Acceptability and Determinants for Implementation of the EnzySystem, a Novel Near‐Patient Testing Platform for Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Coagulation testing in haemophilia A is limited by the scarcity of testing facilities capable of performing relevant assays. This issue incentivized the development of the EnzySystem for haemophilia A, a near‐patient testing platform aimed to measure Factor VIII activity and thrombin generation simultaneously within 1 h from 100 ...
Aernoud P. Bavinck, Kyle Davis, Lisa van Engelshoven, Monique G. van Lier, Tanja Hamacher, Nicole M. A. Blijlevens, Amy Shapiro, Saskia E. M. Schols, Waander L. van Heerde   +8 more
wiley   +1 more source

Factor IX Padua for haemophilia B gene addition: universal adaptation and repeated success. [PDF]

Lancet Haematol, 2022
George LA.
europepmc   +1 more source

The Treatment of Haemophilia A and B and von Willebrand's Disease [PDF]

, 1978
D I Evans
openalex   +1 more source

Initial Presentation of Haemophilia B in a 3-month-old Infant - A Case Report and Literature Review [PDF]

, 2022
Huda Mohamed, Nada Ghazy, Heba AlAmiri, Hasa AlNuaimi, Aysha Al-Kaabi, Haydar AlRufaye   +5 more
openalex   +1 more source