Results 21 to 30 of about 12,413,959 (307)
Perioperative replacement therapy in haemophilia B: An appeal to “B” more precise [PDF]
Haemophilia, 2018 Haemophilia B is caused by a deficiency of coagulation factor IX (FIX) and characterized by bleeding in muscles and joints. In the perioperative setting, patients are treated with FIX replacement therapy to secure haemostasis.
H. Hazendonk +14 more
semanticscholar +2 more sources
Characteristics and Treatment Patterns of Patients with Haemophilia B Receiving Recombinant Coagulation Factor IX. [PDF]
J Clin MedPark YS +16 more
europepmc +3 more sources
Haemophilia B is clinically less severe than haemophilia A: further evidence. [PDF]
Blood Transfus, 2018 Preview Haemophilia A and B are rare bleeding disorders caused by mutations in the genes encoding coagulation factor VIII (FVIII) and factor IX (FIX)1. The prevalence of haemophilia A is 1 in 5,000 males in the general population, while that of haemophilia B is 1 in 40,0001,2.
Franchini M, Mannucci PM.
europepmc +3 more sources
Promoterless gene targeting without nucleases ameliorates haemophilia B in mice
Nature, 2014 Adi Barzel +10 more
exaly +2 more sources
Prophylaxis use among males with haemophilia B in the United States. [PDF]
Haemophilia, 2017 Ullman M +5 more
europepmc +2 more sources
Impact of Functional Disability on Quality of Life in Patients with Haemophilia: An Observational Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Haemophilia is a disease characterised by multiple episodes of spontaneous as well as traumatic bleeding leading to joint pains, joint damage.
Ashish Kavi +3 more
doaj +1 more source
Gene Therapy in Hemophilia: A Transformational Patient Experience
Journal of Patient Experience, 2023 Hemophilia is a bleeding disorder caused by a single absent/defective gene and characterized by a lack of functional clotting factors. People with hemophilia may experience joint damage, pain, and psychological impairments, all of which could contribute ...
Enayet Rasul +7 more
doaj +1 more source
The B-team: Equal but different?
The Journal of Haemophilia Practice, 2021 As a person with haemophilia B, I have known there are differences between haemophilia A and haemophilia B and their respective treatment throughout my life – though I was shocked when I learnt about the impact inhibitors can have when it comes to ...
Pembroke Luke
doaj +1 more source
South African Family Practice, 2022 Background: Haemophilia A and B are X-linked recessive bleeding disorders resulting from a deficiency of factors VIII and IX, respectively. Early diagnosis and a comprehensive approach to management is mandatory.
Lethukuthula Mafisa +2 more
doaj +1 more source
Haemophilia, 2022 Haemophilia B patients with factor IX inhibitors have particularly unmet needs for conventional therapy.
M. Sakai +12 more
semanticscholar +1 more source