Results 21 to 30 of about 9,259 (230)
Unexpected haemophilia despite pre‐natal testing – a combined haemophilia A and haemophilia B family [PDF]
British Journal of Haematology, 2017 Noémi Roy, Nicola Curry, David Keeling
openalex +4 more sources
Utilization evaluation of factor concentration and frequencyof bleeds among patients with haemophilia "A" and haemophilia "B" in northwest Iran [PDF]
Journal of Analytical Research in Clinical Medicine, 2013 Background Haemophilia A and B are X-linked bleeding disorders which result in decreased blood levels of coagulants. According to some studies, Hemophilia Severity Score (HSS) is higher in severe Haemophilia A(HA) than in severe Haemophilia B(HB ...
Roya Dolatkhah +5 more
doaj +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Molecular Profiling of FIX (FACTOR 9) Gene of Hemophilia B in Karnataka
BLDE University Journal of Health Sciences, 2020 Introduction: Haemophilia is one of the “Bleeder Disorder” that causes abnormal bleeding or poor blood clotting. It occurs due to the defect in the clotting factors even in their functions and in some cases structures are altered.
Sujayendra Kulkarni +6 more
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Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo. [PDF]
PLoS ONE, 2017 Canine models of severe haemophilia resemble their human equivalents both regarding clinical bleeding phenotype and response to treatment. Therefore pre-clinical studies in haemophilia dogs have allowed researchers to make valuable translational ...
Daniel Elenius Madsen +4 more
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Medicina, 2021 We present the case of a 70-year-old man with a history of haemophilia B, who presented to our hospital with a non-ST-elevation myocardial infarction.
Konstantinos C. Theodoropoulos +6 more
doaj +1 more source
BMJ Open, 2021 Introduction Two meta-analyses showed lower bone mineral density (BMD) in patients with haemophilia (haemophilia type and severity were often not specified) compared with healthy controls.
Brigitte Tardy‐Poncet +7 more
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Clinical profile of children with haemophilia at the University Hospital of Brazzaville
The Journal of Haemophilia Practice, 2020 Haemophilia is a rare hereditary haemorrhagic disease caused by coagulation factor VIII (haemophilia A) or IX (haemophilia B) deficiency. Very few data exist on this disease in Congo.
Galiba Atipo Tsiba FO +5 more
doaj +1 more source
The Journal of Haemophilia Practice, 2022 Haemophilia is an inherited X-linked bleeding disorder characterised by a deficiency or absence of clotting factor VIII (haemophilia A) or IX (haemophilia B), which can cause musculoskeletal bleeding. The standard treatment for haemophilia is with factor
Das Arijit +3 more
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The use of rIX-FP in patients with haemophilia B: a nurse's perspective
The Journal of Haemophilia Practice, 2021 The management of patients with haemophilia is complex and requires lifelong care to be delivered by a specialist multidisciplinary team. Haemophilia B results from a deficiency or absence in coagulation factor IX (FIX), leading to easy bruising, and ...
Garner Kara +2 more
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