Results 111 to 120 of about 194,983 (307)

Haemophilus Responses to Nutritional Immunity: Epigenetic and Morphological Contribution to Biofilm Architecture, Invasion, Persistence and Disease Severity

PLoS Pathogens, 2013
In an effort to suppress microbial outgrowth, the host sequesters essential nutrients in a process termed nutritional immunity. However, inflammatory responses to bacterial insult can restore nutritional resources.
B. Szelestey, D. R. Heimlich, Forrest K. Raffel, S. Justice, K. Mason   +4 more
semanticscholar   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]

, 2014
Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L, Ehsaan, M, Heap, JT, Knox, R, Kubiak, AM, Kuehne, SA, Lambin, P, Mellaert, LV, Minton, NP, Paesmans, K, Theys, J   +10 more
core   +4 more sources

Absence of an Important Vaccine and Diagnostic Target in Carriage- and Disease-Related Nontypeable Haemophilus influenzae

Clinical and Vaccine Immunology, 2013
Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates.
H. Smith-Vaughan, A. Chang, D. Sarovich, R. Marsh, K. Grimwood, A. Leach, P. Morris, E. Price   +7 more
semanticscholar   +1 more source

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes the Composition of the Oral, But Not the Intestinal Microbiome

Molecular Nutrition &Food Research, EarlyView.
This randomized, double‐blind, and placebo‐controlled crossover study investigated the effects of an increased intake of inorganic nitrate from beetroot juice over 4 weeks on the oral and intestinal microbial communities in older adults with treated high blood pressure.
Rebeka Fejes, Joana Séneca, Petra Pjevac, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Romy Steiner, Karl‐Heinz Wagner, Richard J. Woodman, Catherine P. Bondonno, Jonathan M. Hodgson, David Berry, Michael Wolzt, Oliver Neubauer   +13 more
wiley   +1 more source

Otitis Media Trial Publication After ClinicalTrials.gov Registration

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the proportion of completed otitis media (OM) clinical trials registered on ClinicalTrials.gov and identify factors associated with nonpublication. Study Design Cross‐sectional observational study. Setting ClinicalTrials.gov registry and peer‐reviewed literature databases.
Michael Oca, Suraj M. Rajan, Z. Jason Qian   +2 more
wiley   +1 more source

Haemophilus influenzae type b meningitis in a vaccinated and immunocompetent child

Journal of Infection and Public Health, 2017
Invasive Haemophilus influenzae type b (Hib) disease decreased dramatically after the introduction of conjugate vaccine in routine immunization schedules.We report a case of a fifteen-months-old girl, previously healthy and vaccinated, admitted in the ...
Ana F. Almeida, Eunice Trindade, Artur B. Vitor, Margarida Tavares   +3 more
doaj   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Microbiota diversity and differences in the respiratory tract of children with pneumonia

Pediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge, Lingyun Hou, Jintao Guo, Xuejing Lv, Yungang Yang   +4 more
wiley   +1 more source

EFFICIENCY AND SAFETY OF VACCINATION AGAINST INFECTION CAUSED BY HAEMOPHILUS INFLUENZAE TYPE B AMONG INFANTS

Педиатрическая фармакология, 2008
The authors studied the results of immunization among the children against the infection caused by haemophilus influenzae type B by two vaccines: ACT HIB and Hiberix.
V.V. Botvin’eva, L.S. Namazova, A.G. Gaivoronskaya, E.G. Filyanskaya   +3 more
doaj   +2 more sources