Phase I, randomized, observer-blind, placebo-controlled studies to evaluate the safety, reactogenicity and immunogenicity of an investigational non-typeable Haemophilus influenzae (NTHi) protein vaccine in adults [PDF]
, 2016 Background: Non-typeable Haemophilus influenzae (NTHi) is a major cause of various respiratory diseases. The development of an effective vaccine against NTHi mandates new approaches beyond conjugated vaccines as this opportunistic bacterium is non ...
Aris, Emmanuel +7 more
core +2 more sources
The ISME Journal, 2019 Aggregatibacter and Haemophilus species are relevant human commensals and opportunistic pathogens. Consequently, their bacteriophages may have significant impact on human microbial ecology and pathologies.
S. Szafrański +6 more
semanticscholar +1 more source
Microbiome, 2018 While almost all infants are infected with respiratory syncytial virus (RSV) before the age of 2 years, only a small percentage develops severe disease. Previous studies suggest that the nasopharyngeal microbiome affects disease development. We therefore
T. Ederveen +9 more
semanticscholar +1 more source
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +3 more sources
Analysis of the Effects of Dietary Pattern on the Oral Microbiome of Elite Endurance Athletes [PDF]
, 2019 Although the oral microbiota is known to play a crucial role in human health, there are few studies of diet x oral microbiota interactions, and none in elite athletes who may manipulate their intakes of macronutrients to achieve different metabolic ...
Burke, Louise M +8 more
core +3 more sources
Predicting bacteria causing acute bacterial rhinosinusitis by clinical features
Brazilian Journal of Otorhinolaryngology, 2020 Introduction: Clinicians rely on clinical presentations to select therapeutic agents for acute bacterial rhinosinusitis. Streptococcus pneumoniae and Haemophilus influenzae are common in acute bacterial rhinosinusitis.
Dussawan Suwannawong +7 more
doaj +1 more source
Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]
, 2018 To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina +10 more
core +1 more source
Future Microbiology, 2017 AIM To design a highly specific and sensitive multiplex real-time PCR assay for the differentiation of the pathogen Haemophilus influenzae from its nonpathogenic near-neighbor Haemophilus haemolyticus.
E. Price +7 more
semanticscholar +1 more source
Synthesis and Application of Bioactive N‐Functionalized Aziridines
Angewandte Chemie, EarlyView.This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan +4 more
wiley +2 more sources
Isolation of Haemophilus influenzae from Urine of an Elderly Male Patient with Carcinoma Bladder-An Under-recognised Pathogen? [PDF]
Journal of Clinical and Diagnostic Research, 2018 Haemophilus species are rare uropathogens. The incidence and significance of Haemophilus species isolated from the genitourinary tract are not well studied.
Ramya Raghavan +2 more
doaj +1 more source