Results 31 to 40 of about 96,949 (272)

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Carriage of Haemophilus influenzae in the Pre- and Post-Hib Vaccine Eras Revisited: A Systematic Review and Meta-Analysis

Vaccines
Background/Objectives: Re-emergence of Haemophilus influenzae serotype b (Hib) was reported in several European countries. We aimed to characterize the age distribution of H. influnezae carriage before and after Hib vaccination.
Samy Taha, Nouria Belkacem, Ala-Eddine Deghmane, Muhamed-Kheir Taha   +3 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Resurgence of invasive Haemophilus influenzae type b disease in France, 2017–2024: epidemiological, genomic, and immunological insights

npj Vaccines
Haemophilus influenzae type b (Hib) conjugate vaccines have markedly reduced global invasive Hib disease. However, surveillance in France has shown a resurgence of Hib infections in children despite >90% vaccination coverage, coinciding with the shift ...
Nouria Belkacem, Samy Taha, Aude Terrade, Oumar Doucoure, Mélanie Denizon, Eva Hong, Michael Pruvost, Muhamed-Kheir Taha, Ala-Eddine Deghmane   +8 more
doaj   +1 more source

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Evaluation of VITEK 2 system and VITEK MS system for the identification of Haemophilus species: a diagnostic accuracy study

Annals of Clinical Microbiology
Background: Haemophilus is an important pathogen in community-acquired pneumonia and invasive diseases, such as sepsis and meningitis. We aimed to evaluate the VITEK 2 system and VITEK MS system for the identification of Haemophilus strains isolated from
Yeon Chan Choi, Eun-Young Kim, Hyun Jin Choi, Si Hyun Kim, Eunkyoung You, Ja Young Lee, Jihyun Cho, Seok Hoon Jeong, Dokyun Kim, Hyun Soo Kim, Soo Hyun Kim, Young Ah Kim, Young Ree Kim, Nam Hee Ryoo, Jong Hee Shin, Kyeong Seob Shin, Young Uh, Jeong Hwan Shin   +17 more
doaj   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

Equine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule, Babiche Heil, Jamie K. Norris, Kristene Gedye, Xiaoxiao Lin, Ward De Spiegelaere, Peter Daels, Pouya Dini   +7 more
wiley   +1 more source

Exploratory analysis of potential association between oral Haemophilus and sleep disturbances in major depressive disorder patients

Frontiers in Cellular and Infection Microbiology
BackgroundThe current study aimed to explore the specific oral microbiota profiles in major depressive disorder (MDD) patients with sleep disturbances, and to evaluate the potential mechanisms by which oral microbiota may be implicated in MDD ...
Yachen Shi, Yachen Shi, En Zhao, Weigang Gong, Qianqian Gao, Yang Li, Yang Li, Guangjun Xi, Guangjun Xi, Yan Han, Yan Han, Hui Weng, Feng Wang, Feng Wang, Feng Geng, Gaojia Zhang, Gaojia Zhang   +16 more
doaj   +1 more source

The Role of α-Defensins 1–3 in Antimicrobial Protection Forming in Children with Recurrent Bronchitis Caused by Bacteria of the Genus Haemophilus

Zdorovʹe Rebenka, 2013
The level of α-defensins 1–3 (HNP 1–3) has been analyzed in the blood plasma of children with recurrent bronchitis caused by bacteria of the genus Haemophilus.
G.O. Lezhenko, O.Ye. Abaturov, O.Ye. Pashkova, L.I. Pantyushenko   +3 more
doaj   +1 more source