Results 41 to 50 of about 51,657 (175)

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

Acta Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz, Raz Somech, Dan Dominissini, Nathan Keller, Efrat Dresner, Michal Paret, Gilad Sherman, Guy Katzenellenbogen, Elina Gelman, Keren Asraf, Ram Doolman, Atar Lev, Amos J. Simon, Helly Vernitsky, Assaf Barg, Hana Golan, Amos Toren, Michal Stein   +17 more
wiley   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae

Genome Medicine
Background Haemophilus influenzae is an opportunistic bacterial pathogen that can cause severe respiratory tract and invasive infections. The emergence of β-lactamase-negative ampicillin-resistant (BLNAR) strains and unclear correlations between ...
Margo Diricks, Sabine Petersen, Lennart Bartels, Thiên-Trí Lâm, Heike Claus, Maria Paula Bajanca-Lavado, Susanne Hauswaldt, Ricardo Stolze, Omar Jiménez Vázquez, Christian Utpatel, Stefan Niemann, Jan Rupp, Inken Wohlers, Matthias Merker   +13 more
doaj   +1 more source

The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review

Journal of Infection and Public Health, 2014
Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture.
Prashant Purohit, Ina’am Ahmad Al-Obaid, Nehad Gamal Al-Deen Omar   +2 more
doaj   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

EFFICIENCY AND SAFETY OF VACCINATION AGAINST INFECTION CAUSED BY HAEMOPHILUS INFLUENZAE TYPE B AMONG INFANTS

Педиатрическая фармакология, 2008
The authors studied the results of immunization among the children against the infection caused by haemophilus influenzae type B by two vaccines: ACT HIB and Hiberix.
V.V. Botvin’eva, L.S. Namazova, A.G. Gaivoronskaya, E.G. Filyanskaya   +3 more
doaj   +2 more sources

Assessing the Reduction of Recurrent Admissions Using OM‐85 for the Treatment of Preschool Wheeze (ARROW): Protocol for a Multi‐Centre, Randomised, Double‐Blind, Placebo‐Controlled Trial

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims Acute wheezing illnesses are among the most common reasons preschool‐aged children are admitted to hospital. Readmission rates are high, and novel preventive strategies are required. OM‐85 is an orally administered bacterial lysate that stimulates anti‐viral immune responses and reduces excessive airway inflammation associated with ...
Jessica C. Costa‐Pinto, Marisa van Arragon, Katherine J. Lee, Lisa Gold, Peter D. Sly, Cameron C. Grant, Sarah McNab, Peter Vuillermin, Children's Inpatient Research Collaboration of Australia and New Zealand (CIRCAN) Investigator Group, Rebecca Alekzander, Ravichandra Balakrishnamoorthy, Sean Beggs, Habib Bhurawala, Stewart Birt, Katie Bongiolatti, Stephen Brancatisano, Blessy Charles, Roni Cole, Jessica C. Costa‐Pinto, Bailey Craig, Jacqueline Dalby‐Payne, Taya Dowling, Chris Elliot, Daniel Engleman, Wei Qi Fan, Alice Fang, Jane Fata, Catriona Fleming, Jacqueline Fradley, Jeremy Furyk, Arun Gangakhedkar, Lisa Gold, Angus Goodson, Peter Gowdie, Cameron Grant, Kelly Grant, Shehani Gunasekera, Louise Guy, Danielle Hanlon, Rachael Healey, Reena Ho, Sharon Jones, Datta Joshi, Vishal Kapoor, Jonathan Kaufman, Elizabeth Kepreotes, Annie Kilpatrick, Helena Kim, Kristy Kimlin, Christine Kwa, Julia Laing, Anita Lala, Malia Lardelli, Christine Lau, Shirley Lawrence, Katherine J. Lee, Rachel Lee, Jordan Levinter, David Levitt, Hannah Lorking, Lorraine Torrance, April Ly, Ariel Mace, Maricar Santiago Maminta, Payal Mandaliya, Natalie Martin, Brendan McCann, Timothy McDonald, Richard G. McGee, Kathryn McMahon, Sarah McNab, Kristen Mead, Tania Milne, Vasemaca Moi, Nerida Moore, Dylan Mordaunt, Tanya Newnham, Mark Norden, Kirra Philip, Maree Pigdon, Melanie Pillay, Michael Plaister, Jolene Reid, Julia Reid, Nicholas Reid, Kathryn Roberts, Maria Ronan, Thomas Saunders, Jennifer Schaefer, Rachel Schembri, Leonie Shah, Owen Sinclair, Peter Sly, Gail Spence, Jane Standish, Alicia Stanley, Simon Stokes, Scott Sypek, Laurel Teoh, Rachel Teulon, Clare Thomas, David Tickell, Laarni Tundag, Marisa Van Arragon, Peter Vuillermin, Ushma Waida, Matthew Wakeley, Alexandra Wallace, Todd Wallace, Simone Watkins, Ben Watson, Cilla Wyllie‐Schmidt, Rose Ann Yap, Helen Young, Joel Ziffer   +114 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source