Results 31 to 40 of about 51,556 (181)

Emergence of antimicrobial resistance among invasive Haemophilus influenzae isolates in Belgium: epidemiology and genomic characterization

International Journal of Infectious Diseases
Introduction: Haemophilus influenzae (Hi) is a significant cause of invasive infections, including meningitis and sepsis. The emergence of resistant strains has prompted the World Health Organization to include Hi on its priority list for research and ...
Ms Magali Wautier, Dr Ricardo El Nouwar, Mr Benoit Prevost, Ms Farida Ahajjam, Ms Ariane Deplano, Ms Rim Fekkak, Dr Nicolas Yin, Dr Maya Hites, Prof Delphine Martiny   +8 more
doaj   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Haemophilus influenzae type b meningitis in a vaccinated and immunocompetent child

Journal of Infection and Public Health, 2017
Invasive Haemophilus influenzae type b (Hib) disease decreased dramatically after the introduction of conjugate vaccine in routine immunization schedules.We report a case of a fifteen-months-old girl, previously healthy and vaccinated, admitted in the ...
Ana F. Almeida, Eunice Trindade, Artur B. Vitor, Margarida Tavares   +3 more
doaj   +1 more source

Clinical characteristics of bacteremia caused by Haemophilus and Aggregatibacter species and antimicrobial susceptibilities of the isolates

Journal of Microbiology, Immunology and Infection, 2021
Background/purpose: This study aimed to investigate the clinical characteristics and outcomes of bacteremia caused by Haemophilus and Aggregatibacter species in patients who were treated at a medical center between 2006 and 2018. Methods: Haemophilus and
Ying-Chun Chien, Yu-Tsung Huang, Chun-Hsing Liao, Jung-Yien Chien, Po-Ren Hsueh   +4 more
doaj   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Incidence of Haemophilus influenzae type b among children less than 5 years and resistance to antibiotics in Iraq.

مجلة كلية الطب, 2015
Back ground: Meningitis is an inflammation of the protective membranes covering the brain and spinal cord that known as meninges. It is the major cause of morbidity and mortality among infants and children less than the age of 5 years.
Maha F. Almelan
doaj   +1 more source

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

Investigating the Presence of Haemophilus Influenzae in Patients with Chronic Obstructive Pulmonary Disease (COPD) Using Molecular Method

مجله دانشکده پزشکی اصفهان, 2019
Background: Chronic obstructive pulmonary disease (COPD) is a type of obstructive pulmonary disease characterized by chronic airway blockage. The aim of this study was to investigate the presence of Haemophilus influenzae in patients with COPD using ...
Hedeyeh Mohaghegh-Mortazavi, Naghmeh Bahrami, Tahereh Naji, Abdolreza Mohamadnia   +3 more
doaj   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source