Results 31 to 40 of about 25,084 (169)

Shielding of a Lipooligosaccharide IgM Epitope Allows Evasion of Neutrophil-Mediated Killing of an Invasive Strain of Nontypeable Haemophilus influenzae

open access: yesmBio, 2014
Nontypeable Haemophilus influenzae is a frequent cause of noninvasive mucosal inflammatory diseases but may also cause invasive diseases, such as sepsis and meningitis, especially in children and the elderly.
Jeroen D. Langereis, Jeffrey N. Weiser
doaj   +1 more source

Carriage of Haemophilus influenzae in the Pre- and Post-Hib Vaccine Eras Revisited: A Systematic Review and Meta-Analysis

open access: yesVaccines
Background/Objectives: Re-emergence of Haemophilus influenzae serotype b (Hib) was reported in several European countries. We aimed to characterize the age distribution of H. influnezae carriage before and after Hib vaccination.
Samy Taha   +3 more
doaj   +1 more source

Polyarticular Septic Arthritis Due to Non-Typeable With Concomitant New-Onset Acute Gouty Arthritis

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2019
Haemophilus influenzae is serologically classified into two main categories based on the presence or absence of the polysaccharide capsule. Strains that possess polysaccharide capsules are identified as typeable Haemophilus influenzae , whereas strains ...
Brian Sanders MD   +3 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

open access: yesAdvanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch   +6 more
wiley   +1 more source

Role of biofilm formation and antimicrobial resistance in urogenital Haemophilus influenzae isolates

open access: yesBMC Microbiology
Background Haemophilus influenzae (Hi) is increasingly detected in genital infections in humans and linked to septic abortion. We aimed to characterize 123 non-capsulated (non-typeable) Hi isolates from genital sites in women and investigate their ...
Nouria Belkacem   +4 more
doaj   +1 more source

Multi-Component Vaccine Candidates Against Non-Typeable Haemophilus influenzae

open access: yesVaccines
Background: Haemophilus influenzae (Hi), a Gram-negative bacterium, is divided into two broad categories: encapsulated and non-capsulated isolates, also called non-typeable Hi isolates (NTHi).
Nouria Belkacem   +2 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi   +6 more
wiley   +1 more source

Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007-2014 [PDF]

open access: yes, 2017
European Centre for Disease Prevention and Control Country Experts for Invasive Haemophilus influenzae Disease: INSA - Paula LavadoWe describe the epidemiology of invasive Haemophilus influenzae disease during 2007-2014 in 12 European countries and ...
Whittaker, Robert   +9 more
core   +1 more source

Multi-Antigen Protein Vaccine Confers Protection in a Murine Model Against Intranasal Haemophilus influenzae Challenge

open access: yesVaccines
Background: Non-typeable Haemophilus influenzae (NTHi) is a major cause of acute respiratory tract infections and chronic airway disease, despite its clinical importance, no licensed vaccine is available, largely due to the extensive genetic and ...
Nouria Belkacem   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy