Results 21 to 30 of about 100,736 (214)

Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1beta Release by Pulmonary Epithelial Cells [PDF]

, 2018
Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood.
Grau, Veronika, Koch, Christian, Magel, Ilona, McIntosh, J. Michael, Padberg, Winfried, Perniss, Alexander, Richter, Katrin, Sander, Michael, Schweda, Elke K. H., Wichmann, Sven, Wilker, Sigrid, Wolf, Philipp M.   +11 more
core   +1 more source

How do nematodes transfer phosphorylcholine to carbohydrates? [PDF]

, 2010
An unusual aspect of the biology of nematodes is the attachment of phosphorylcholine (PC) to carbohydrate. The attachment appears to play an important role in nematode development and, in some parasitic species, in immunomodulation.
Harnett, W., Houston, K.M., Rzepecka, J.
core   +1 more source

Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD. [PDF]

, 2017
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder partially resistant to glucocorticoids. A reduced histone deacetylase (HDAC) activity has been proposed to explain this resistance.
Agustí García-Navarro, Àlvar, Busquets, Xavier, Cosío, Borja G., Iglesias, Amanda, Jahn, Andreas, Shafiek, Hanaa   +5 more
core   +1 more source

Shielding of a Lipooligosaccharide IgM Epitope Allows Evasion of Neutrophil-Mediated Killing of an Invasive Strain of Nontypeable Haemophilus influenzae

mBio, 2014
Nontypeable Haemophilus influenzae is a frequent cause of noninvasive mucosal inflammatory diseases but may also cause invasive diseases, such as sepsis and meningitis, especially in children and the elderly.
Jeroen D. Langereis, Jeffrey N. Weiser
doaj   +1 more source

Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples. [PDF]

, 2014
Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current ...
Adegbola, Richard A, Antonio, Martin, Briese, Thomas, Chimah, Osaretin, Corrah, Tumani, Dione, Michel, Ebruke, Bernard E, Greenwood, Brian, Hill, Philip C, Howie, Stephen RC, Ideh, Readon C, Jallow, Mariatou, Lipkin, W Ian, Machuka, Eunice M, Morris, Gerard AJ, Mulholland, Kim, Njie, Malick, Oluwalana, Claire, Secka, Ousman, Tokarz, Rafal, Townend, John   +20 more
core   +1 more source

Conservation of structure and mechanism in primary and secondary transporters exemplified by SiaP, a sialic acid binding virulence factor from Haemophilus influenzae [PDF]

, 2006
Extracytoplasmic solute receptors (ESRs) are important components of solute uptake systems in bacteria, having been studied extensively as parts of ATP binding cassette transporters.
Kelly, D.J., Muller, A., Mulligan, C., Severi, E., Thomas, G.H., Watts, A.G., Wilkinson, A.J., Wilson, K.S.   +7 more
core   +2 more sources

Polyarticular Septic Arthritis Due to Non-Typeable With Concomitant New-Onset Acute Gouty Arthritis

Journal of Investigative Medicine High Impact Case Reports, 2019
Haemophilus influenzae is serologically classified into two main categories based on the presence or absence of the polysaccharide capsule. Strains that possess polysaccharide capsules are identified as typeable Haemophilus influenzae , whereas strains ...
Brian Sanders MD, Mohammed Abdulfatah MD, Mossab Aljuaid MD, Ibrahim Tawhari MD, MPH   +3 more
doaj   +1 more source

Vaccine coverage and determinants of incomplete vaccination in children aged 12-23 months in dschang, west region, cameroon: a cross-sectional survey during a polio outbreak [PDF]

, 2015
Inadequate immunization coverage with increased risk of vaccine preventable diseases outbreaksremains a problem in Africa. Moreover, different factors contribute to incomplete vaccination status. This study wasperformed in Dschang (West Region, Cameroon),
Biguioh, Rodrigue Mabvouna, Bouting Mayaka, Georges, Miglietta, Alessandro, Pezzotti, Patrizio, Rezza, Giovanni, Russo, Gianluca, Sobze, Martin Sanou, Stefanelli, Paola, Vullo, Vincenzo   +8 more
core   +2 more sources

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

American Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini   +38 more
wiley   +1 more source

Role of Haemophilus influenzae in Formation of Infectious Diseases in Children

Zdorovʹe Rebenka, 2013
The paper contains an analysis and synthesis of current views on the role of Haemophilus influenzae in the formation of infectious diseases in children.
G.O. Lezhenko, O.Ye. Pashkova, L.I. Pantyushenko   +2 more
doaj   +1 more source