Results 21 to 30 of about 39,488 (201)
Jornal de Pediatria, 2006 OBJETIVO: Identificar as evidências sobre o impacto da vacina conjugada para Haemophilus influenzae tipo b (Hib) na epidemiologia da doença invasiva por Hib.
Cristiana M. Nascimento-Carvalho +1 more
doaj +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Advanced Science, EarlyView.Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu +11 more
wiley +1 more source
Invasive Disease Caused by Nontypeable Haemophilus influenzae
Emerging Infectious Diseases, 2015 The incidence of severe Haemophilus influenza infections, such as sepsis and meningitis, has declined substantially since the introduction of the H. influenzae serotype b vaccine. However, the H.
Jeroen D. Langereis, Marien I. de Jonge
doaj +1 more source
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To determine whether diabetes mellitus is associated with higher systemic and hip‐specific complications and to evaluate reoperation rates after hip arthroscopy. Methods Using the TriNetX Research Network and Current Procedural Terminology and International Classification of Diseases codes, we identified diabetic and nondiabetic patients aged ...
Nicholas J. Morriss +3 more
wiley +1 more source
Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access
Clinical Pharmacology &Therapeutics, EarlyView.Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian +5 more
wiley +1 more source
Case Reports in Infectious Diseases, 2021 Implementation of the Haemophilus influenzae type B (Hib) conjugate vaccine brought about a reduction in the number of cases and morbidity from type B but an increase in nontypeable strain infections.
Erdem Gönüllü +6 more
doaj +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.This study verified the analytical performance of the fully automated Mindray MN2880 system for the simultaneous detection of SARS‐CoV‐2, influenza A/B viruses, and RSV in 2852 oropharyngeal swab specimens, following CNAS‐GL039:2019, CNAS‐GL037:2019, and ISO 15189:2022 guidelines.
Jinliang Chen +3 more
wiley +1 more source
Epidemiological Monitoring and Prevention of Haemophilus influenzae type b in the RF
Журнал инфектологии, 2014 At three study sites, incidence rates of meningitis caused by Haemophilus influenzae type b exceeded the threshold of 10 cases per на 100,000 children under 5 and mandated vaccination. Both vaccines the use of which is permitted in the Russian Federation
E. Ya. Frolova, V. N. Filatov
doaj +1 more source
Med Research, EarlyView.In 2023, marked regional heterogeneity was observed across Asia: South Asia carried the highest incidence and prevalence, Central Asia had the highest DALY rate, Southeast Asia bore the highest mortality and East Asia and High‐income Asia‐Pacific generally had lower rates.
Lingxia Zhang +13 more
wiley +1 more source